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中华普通外科学文献(电子版) ›› 2009, Vol. 03 ›› Issue (02) : 42 -43. doi: 10.3877/cma.j.issn.1674-0793.2009.02.014

论著

强脉冲光联合维拉帕米颜面外伤早期抗瘢痕治疗
王丽妮1,(), 吴卓桐1, 范锟铻1, 张灵1   
  1. 1.518035 深圳市第二人民医院整形美容科
  • 收稿日期:2008-12-19 出版日期:2009-04-01
  • 通信作者: 王丽妮
  • 基金资助:
    深圳市科技计划资助(200803045)

Earlier treatment of facial injury against scars with intense pulsed light and verapamil

Li-ni WANG1,(), Zhuo-tong WU1, Kun-wu FAN1, Ling ZHANG1   

  1. 1.Centre of Esthetic&Plastic Surgery,Shenzhen Second Hospital,Shenzhen,518035,China
  • Received:2008-12-19 Published:2009-04-01
  • Corresponding author: Li-ni WANG
引用本文:

王丽妮, 吴卓桐, 范锟铻, 张灵. 强脉冲光联合维拉帕米颜面外伤早期抗瘢痕治疗[J]. 中华普通外科学文献(电子版), 2009, 03(02): 42-43.

Li-ni WANG, Zhuo-tong WU, Kun-wu FAN, Ling ZHANG. Earlier treatment of facial injury against scars with intense pulsed light and verapamil[J]. Chinese Archives of General Surgery(Electronic Edition), 2009, 03(02): 42-43.

目的

应用强脉冲光联合维拉帕米行颜面外伤早期预防和抗瘢痕治疗。

方法

75例颜面外伤的患者随机分成3组,每组25例。A组在瘢痕内注射维拉帕米;B组应用强脉冲光照射治疗;C组应用强脉冲光照射治疗后,瘢痕内注射维拉帕米,各组治疗均坚持3次,每次间隔3周。观察治疗后各组外伤的愈合情况。

结果

A组25例患者中,6例痊愈,13例有效,6例无效;B组6例痊愈,12例有效,7例无效;C组13例痊愈,10例有效,2例无效,与其他两组比较,强脉冲光子治疗仪联合维拉帕米治疗效果好,痊愈率高,差异有高度统计学意义(P <0.01)。

结论

强脉冲光联合维拉帕米行颜面外伤早期预防和抗瘢痕治疗是一种疗效好的方法。

Objective

To disscuss the treatment of preventing and resisting scars in facial injuries during earlier period by application of intense pulsed light in conjunction with verapamil.

Methods

Seventy-five patients with facial injuries were randomly divided into three groups,25 cases for each group.Group A were injected with verapamil in scars,group B were applied intense pulsed light irradiation treatment,group C were injected with verapamil in scars after application of intense pulsed light irradiation treatment.All cases were treated three times with three weeks intervals.trauma healing information in each group after treatment were collectected.

Results

Among 25 patients of group A,6 cases were recovered,13 cases were effective,6 cases were invalid,There were 6 cases recovered,12 cases effective,7 cases invalid in group B,and in group B,13 cases were recovered,10 cases were effective, 2 cases were invalid. Compared to group A and B, group C had a better effect, and higher cure rate,P <0.01.

Conclusions

Treatment of preventing and resisting scars in facial injuries during earlier period by application of intense pulsed light in conjunction with verapamil is a eutherapeutic approach.

表1 75 例颜面外伤的患者不同治疗后的疗效比较[例(%)]
1
陈洪,农晓琳.皮肤瘢痕治疗进展.广西医学, 2006, 28(8): 1232-1235.
2
刘流.瘢痕治疗现状.昆明医学院学报,2006,27(4):125-129.
3
李荟元,鲁开化,郭树忠,等.新编瘢痕学.西安:第四军医大学出版社,2003:89.
4
Herd Rm, Dover Js, Arndt Ka, et al. Basic laser principles.Laser in Dermatology.Dermatol Clin,1997,15(3):355.
5
Feugate JE, Wong L, Li QJ, et al. The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts,accelerating development of granulation tissue. BMC Cell Biol, 2002,3(13):13.
6
王元洪,王现国.CO2 激光联合复方倍他米松局部注射治疗瘢痕疙瘩56 例疗效观察.山东医药,2006,46(6):36.
7
罗旭松,林新瑜,向雪岑,等.瘢痕疙瘩治疗研究的新进展.中华医学美容杂志,2003,9(6):122.
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