目的

讨论非功能性胰岛细胞瘤的诊断和治疗。

方法

对收治的6 例此病患者的临床资料进行回顾性分析。

结果

本组6 例经影像学检查后，均接受手术治疗，5 例经手术后病理诊断确诊为恶性肿瘤，3 例经手术治疗后，配合化疗，现仍然存活，2 例死于手术后肿瘤转移；1例为良性肿瘤，现已失访。

结论

本病的诊断主要依赖影像学检查以及胰腺内分泌功能的实验室检查，由于缺乏特异性临床表现，使早、中期确诊困难，晚期常因腹部包块、转移病灶而就诊；手术治疗为主要治疗手段，术后配合化疗可能获得一定疗效。

Objective

To study the clinical diagnosis and treatment of nonfunctioning pancreatic islet cell tumors.

Method

Six patients with nonfunctioning pancreatic islet cell tumors were analyzed retrospectively.

Results

All of the 6 cases were treated with surgery after radiological tests.5 cases turned out to be malignant tumors，and 3 were still alive with post-operational adjuvant chemotherapy.2 died from tumor metastasis，and 1 case with benign tumor was out of contact.

Conclusion

Radiological and endocrinological examinations of pancreas are the main approaches for diagnosis of non functional pancreatic islet cell tumors.Patients often come with abdominal mass or metastases in the end stage，and the tumors are difficult to be detected in the early or middle stage for lacking specific clinical manifestation.Surgical resection is the treatment of choice.Post-operational adjuvant chemotherapy may be beneficial.