目的

研究肝脏局灶性结节性增生（FNH）的临床表现、诊断和治疗。

方法

对1995～2005 年收治的39 例FNH 患者进行回顾性分析。

结果

本组患者男性17 例，女性22 例，年龄21～47 岁。主要病史为:慢性腹部隐痛或胀痛14 例，发现腹部包块4 例，无症状而影像学检查发现肝区占位性病变18 例。治疗方法为：手术切除33 例，腹腔镜下活检1 例，2 例细针穿刺病理证实后行微波消融，3 例活检后未予以治疗。本组患者随访未见肿物复发。

结论

本病病程良性经过，预后良好。诊断明确，症状无或者轻微，可以定期随访。手术治疗主要适用于肿物巨大，压迫症状明显，不能排除原发性肝癌或者肝腺瘤的患者。

Objective

To investigate the clinical manifestation， diagnosis and therapy of focal nodular hyperplasia (FNH).

Methods

Retrospective analysis of 39 cases of FNH treated in our hospital from 1995～2005.

Results

Among the 39 patients， 17 were male and 22 were female， with age from 21 to 47 years old. 14 had chronic abdominal pain. In 4 cases， abdomen mass could be found， the other 21 cases were asymptomatic and were detected by image diagnosis methods. of the 39 patients， 33 underwent hepatic resection，1 underwent biopsy under laparoscopy，2 underwent biopsy and percutaneous microwave coagulation，3 underwent biopsy and no therapy. Follow-up data showed that no recurrence happened after resection.

Conclusion

FNH is a benign disease with good prognosis. For patients with confirmed diagnosis and no symptom， no specific therapies are needed. Surgical resection is recommended for patient of huge mass accompanied with apparent symptoms， those malignant diseases or liver adenoma can't be fully excluded.