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中华普通外科学文献(电子版) ›› 2010, Vol. 04 ›› Issue (04) : 380 -384. doi: 10.3877/cma.j.issn.1674-0793.2010.04.022

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讲座与综述

肠远程缺血预处理在心肌缺血/再灌注损伤中的研究进展
温仕宏1, 姚溪1, 刘克玄1   
  1. 1. 510080 广州,中山大学附属第一医院麻醉科
  • 收稿日期:2010-05-25 出版日期:2010-08-01
  • 基金资助:
    国家自然基金资助(30872446)

Remote ischemic preconditioning protects myocardium from ischemia/reperfusion

Shi-hong WEN1, Xi YAO1, Ke-xuan LIU1   

  • Received:2010-05-25 Published:2010-08-01
引用本文:

温仕宏, 姚溪, 刘克玄. 肠远程缺血预处理在心肌缺血/再灌注损伤中的研究进展[J]. 中华普通外科学文献(电子版), 2010, 04(04): 380-384.

Shi-hong WEN, Xi YAO, Ke-xuan LIU. Remote ischemic preconditioning protects myocardium from ischemia/reperfusion[J]. Chinese Archives of General Surgery(Electronic Edition), 2010, 04(04): 380-384.

表1 短暂性肠系膜缺血介导RIPC的相关研究
研究者 缺血预处理的位置 诱导缺血位置 模型 终末点 器官保护作用 可能机制
Gho等[3] 肠系膜和肾 心肌缺血 大鼠 梗死面积 减少梗死面积 神经、体液因素
Schoemaker等[5] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 缓激肽介导和神经通路
Liem等[8] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 增加间质的腺苷水平;神经刺激;心肌腺苷受体的激活
Patel等[9] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 内源性阿片类物质
Wolfrum等[6] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 通过体液缓激肽途径和神经通路激活心肌PKC
Wolfrum等[7] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 降钙素基因相关肽
Tang等[10] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 辣椒素敏感性感觉神经
Xiao等[11] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 辣椒素敏感性感觉神经和NOS
Wang等[12] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 iNOS的作用
Petrishcev等[13] 心肌和肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 非NO机制
Vlasov等[14] 肠系膜 心脏和肠 大鼠 梗死面积 没有心肌保护作用,只产生小肠特殊适应 不是远程预处理而是直接预处理产生的NO
Liem等[15] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 肠系膜缺血腺苷依赖性途径
Huda等[16] 肠系膜 心肌缺血 大鼠 梗死面积 减少梗死面积 基因表达的改变
1
Yellow DM, Downney JM. Preconditioning the myocardium:from cellular physiology to clinical cardiology. Physiol Rev,2003,83(4):1113-1151.
2
Przyklenk K, Bauer B, Ovize M,et al.Regional ischemic preconditioning protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation,1993,87(3):893-899.
3
Gho BCG, Schoemaker RG, Van Den Doel MA,et al. Myocardial protection by brief ischemia in noncardiac tissue. Circulation,1996,94(9):2193-2200.
4
Oxman T, Arad M, Klein R,et al. Limb ischemia preconditions the heart against reperfusion tachyarrhythmia. Am J Physiol,1997,273(4 Pt 2):H1707-1712.
5
Schoemaker RG, van Heijningen CL. Bradykinin mediates cardiac preconditioning at a distance.Am J Physiol Heart Circ Physiol,2000,278(5):H1571-1576.
6
Wolfrum S, Schneider K, Heidbreder M,et al. Remote preconditioning protects the heart by activating myocardial PKC epsilon-isoform. Cardiovasc Res,2002,55(3):583-589.
7
Wolfrum S, Nienstedt J, Heidbreder M,et al. Calcitonin generelated peptide mediates cardioprotection by remote preconditioning.Regul Pept,2005,127(1-3):217-224.
8
Liem DA, Verdouw PD, Ploeg H,et al. Sites of action of adenosine in interorgan preconditioning of the heart.Am J Physiol Heart Circ Physiol,2002,283(1):H29-37.
9
Patel HH, Moore J, Hsu AK,et al. Cardioprotection at a distance: Mesenteric artery occlusion protects the myocardium via an opioid sensitive mechanism. J Mol Cell Cardiol,2002,34(10):1317-1323.
10
Tang ZL, Dai W, Li YJ,et al. Involvement of capsaicinsensitive sensory nerves in early and delayed cardioprotection induced by a brief ischaemia of the small intestine. Naunyn Schmiedebergs Arch Pharmacol,1999,359(3):243-247.
11
Xiao L, Lu R, Hu CP,et al. Delayed cardioprotection by intestinal preconditioning is mediated by calcitonin gene-related peptide. Eur J Pharmacol,2001,427(2):131-135.
12
Wang YP, Xu H, Mizoguchi K,et al. Intestinal ischemia induces late preconditioning against myocardial infarction: A role for inducible nitric oxide synthase. Cardiovasc Res,2001,49(2):391-398.
13
Petrishchev NN, Vlasov TD, Sipovsky VG,et al. Does nitric oxide generation contribute to the mechanism of remote ischemic preconditioning? Pathophysiology,2001,7(4):271-274.
14
Vlasov TD, Smirnov DA, Nutfullina GM. Adaptation of the rat small intestine to ischemia. Ross Fiziol Zh Im I M. Sechenova,2001,87(1):118-124.
15
Liem DA, Te Lintel HM, Manintveld OC,et al. Myocardium tolerant to an adenosine-dependent ischemic preconditioning stimulus can still be protected by stimuli that employ alternative signaling pathways. Am J Physiol Heart Circ Physiol,2005,288(3):H1165-172.
16
Huda R, Chung DH, Mathru M. Ischemic preconditioning at a distance: Altered gene expression in mouse heart and other organs following brief occlusion of the mesenteric artery. Heart Lung Circ,2005,14(1):36-43.
17
Hausenloy DJ, Yellon DM. Preconditioning and postconditioning: united at reperfusion. Pharmacol Ther,2007,116(2):173-191.
18
McClanahan T, Nao B, Wolke L,et al. Brief renal occlusion and reperfusion reduces myocardial infarct size in rabbits.(Abstract). FASEB J,1993,7:A18.
19
Dickson EW, Reinhardt CP, Renzi FP,et al. Ischemic preconditioning may be transferable via whole blood transfusion:preliminary evidence. J Thromb Thrombolysis,1999,8(2):123-129.
20
Dickson EW, Lorbar M, Porcaro WA,et al.Rabbit heart can be'preconditioned’via transfer of coronary effluent.Am J Physiol,1999,277(6 Pt 2):H2451-2457.
21
Dickson EW, Porcaro WA, Fenton RA,et al.'Preconditioning at a distance’ in the isolated rabbit heart. Acad Emerg Med,2000,7(4):311-317.
22
Konstantinov IE, Li J, Cheung MM,et al. Remote ischemic preconditioning of the recipient reduces myocardial ischemia-reperfusion injury of the denervated donor heart via a Katp channel-dependent mechanism. Transplantation,2005,79(12):1691-1695.
23
Patel HH, Moore J, Hsu AK,et al. Cardioprotection at a distance: mesenteric artery occlusion protects the myocardium via an opioid sensitive mechanism. J Mol Cell Cardiol 2002,34(10):1317-1323.
24
Di Filippo C, Rossi F, Rossi S,et al. Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN. J Leukoc Biol,2004,75(3):453-459.
25
Serejo FC, Rodrigues LF Jr, Silva Tavares KC,et al. Cardioprotective properties of humoral factors released from rat hearts subject to ischemic preconditioning.J Cardiovasc Pharmacol,2007,49(4):214-220.
26
Kant R, Diwan V, Jaggi AS,et al. Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases. Mol Cell Biochem,2008,312(1-2):25-31.
27
Addison PD, Neligan PC, Ashrafpour H,et al. Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction. Am J Physiol Heart Circ Physiol,2003,285(4):H1435-1443.
28
Weinbrenner C, Schulze F, Sarvary L,et al. Remote preconditioning by infrarenal aortic occlusion is operative via delta1-opioid receptors and free radicals in vivo in the rat heart. Cardiovasc Res,2004,61(3):591-599.
29
Zhang SZ, Wang NF, Xu J,et al. kappa-Opioid receptors mediate cardioprotection by remote preconditioning.Anesthesiology,2006,105(3):550-556.
30
Hajrasouliha AR, Tavakoli S, Ghasemi M,et al. Endogenous cannabinoids contribute to remote ischemic preconditioning via cannabinoid CB(2) receptors in the rat heart. Eur J Pharmacol,2008,579(1-3):246-252.
31
Singh D, Chopra K. Evidence of the role of angiotensin AT(1) receptors in remote renal preconditioning of myocardium.Methods Find Exp Clin Pharmacol,2004,26(2):117-122.
32
Peralta C, Fernandez L, Panes J,et al. Preconditioning protects against systemic disorders associated with hepatic ischemia-reperfusion through blockade of tumor necrosis factor-induced P-selectin up-regulation in the rat. Hepatology,2001,33(1):100-113.
33
Konstantinov IE, Arab S, Kharbanda RK,et al. The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans. Physiol Genomics,2004,19(1):143-150.
34
Konstantinov IE, Arab S, Li J,et al. The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium.J Thorac Cardiovasc Surg,2005,130(5):1326-1332.
35
Vinten-Johansen J. Postconditioning:a mechanical maneuver that triggers biological and molecular cardioprotective responses to reperfusion. Heart Fail Rev,2007,12(3-4):235-244.
36
Weinbrenner C, Nelles M, Herzog N,et al. Remote preconditioning by infrarenal occlusion of the aorta protects the heart from infarction: a newly identified non-neuronal but PKC-dependent pathway.Cardiovasc Res,2002,55(3):590-601.
37
Heidbreder M, Naumann A, Tempel K,et al. Remote vs.ischaemic preconditioning: the differential role of mitogen-activated protein kinase pathways. Cardiovasc Res,2008,78(1):108-115.
38
Costa AD, Jakob R, Costa CL,et al. The mechanism by which the mitochondrial ATP-sensitive KP channel opening and H2O2 inhibit the mitochondrial permeability transition. J Biol Chem,2006,281(30):20801-20808.
39
Tokuno S, Hinokiyama K, Tokuno K,et al. Spontaneous ischemic events in the brain and heart adapt the hearts of severely atherosclerotic mice to ischemia. Arterioscler Thromb Vasc Biol,2002,22(6):995-1001.
40
Hausenloy DJ, Yellon DM. The mitochondrial permeability transition pore: its fundamental role in mediating cell death during ischemia and reperfusion. J Mol Cell Cardiol,2003,35(4):339-341.
41
Cheung MM, Kharbanda RK, Konstantinov IE,et al. Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol,2006,47(11):2277-2282.
42
Hausenloy DJ, Mwamure PK, Venugopal V,et al. Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomized controlled trial. Lancet,2007,370(9587):575-579.
43
Ali ZA, Callaghan CJ, Lim E,et al.Remote ischemic preconditioning reduces myocardial and renal injury after elective abdominal aortic aneurysm repair: a randomized controlled trial.Circulation,2007,116(11Suppl):I98-105.
44
Andreka G, Vertesaljai M, Szantho G,et al. Remote ischaemic postconditioning protects the heart during acute myocardial infarction in pigs. Heart,2007,93(6):749-752.
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