探讨已婚育龄期女性布-加综合征（B-CS）患者不孕及反复自然流产的原因及治疗原则。

回顾性分析2008年1月至2010年6月我院收治的146例已婚育龄期女性B-CS患者的临床资料。

根据患者的分型及病情，选取不同的手术方式或药物治疗，术后给予0.5~2年的随访：其中有月经异常的56例中有42例恢复正常，有效率为75.0%（42/56）；未育的32例中10例成功妊娠或者生育，治疗后怀孕率为31.3%（10/32）；治疗后血小板明显升高（P<0.05），其中78例已恢复至正常水平；16例治疗前性激素检查均有不同程度的异常，治疗后均明显好转（P<0.05），其中11例恢复正常。

布-加综合征是育龄期妇女不孕不育及反复自然流产的高危因素。及早正确的治疗可以纠正此类患者的月经紊乱和提高受孕率及生育率。

To stduy the reason and therapeutic principles of sterility infertility and recurrent spontaneous abortion in married women of reproductive age with Budd-Chiari syndrome.

The clinical data of 146 female patients with B-CS from January 2008 to June 2010 were reviewed retrospectively.

The surgery methods and drug therapy were selected according to the types and the patient's conditions of the B-CS, following-up half two years postoperation. Fifty-six cases had menstrual disorder history, 42 cases recovered, the cure rate was 75.0%(42/56). Ten cases had a successful pregnancy or fertility, the pregnancy rate was 31.3%(10/32). The platelet levels increased significantly(P<0.05), therein 78 cases recovered. Sixteen cases had sex hormones examination, all of them were abnormal before treatment, improved markedly(P<0.05) and 11 cases recovered.

Budd-Chiari syndrome is a risk factor in women of reproductive age of sterility infertility and recurrent spontaneous abortion.Early and accurate treatment can correct the menstrual disorder of such patients and improve pregnancy rate and fertility rate.