| 1 |
Cammisotto PG, Rensud C, Gingras D, et al. Endocrine and exocrine secretion of leptin by the gastric mucosa[J]. J Histecbem Cytochem, 2005, 53(7): 85l-860．
|
| 2 |
Attoub S, Nce V, Pirola L, et al. Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways[J]. FASEB J, 2000, 14(14): 2329-2338．
|
| 3 |
彭彦霄，陆震，吴学平, 等. 瘦素及其受体在人胚胎小肠不同发育阶段的表达[J].解剖学研究, 2008, 30(1): 32-34．
|
| 4 |
Mackey-Lawrence NM, Petri WA Jr. Leptin and mucosal immunity[J]. Mucosal Immunol, 2012, 5(5): 472-479.
|
| 5 |
Kiely JM, Noh JH, Graewin SJ, et al. Altered intestinal motility in leptin-deficient obese mice[J]. J Surg Res, 2005, 124(1): 98-103．
|
| 6 |
卢静，魏良洲，田字彬, 等. 瘦素与肠动力关系的研究进展[J]. 胃肠病学和肝病学杂志, 2008, 17(1): 83-84.
|
| 7 |
Iqbal J, Li X, Chang BH, et al. An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption[J]. J Lipid Res, 2010, 51(7): 1929-1942.
|
| 8 |
Morton NM, Emilsson V, Liu YL, et al. Leptin action in intestinal cells[J]. J Biol Chem, 1998, 273(40): 26194-26201.
|
| 9 |
Sukhotnik I, Coran AG, Mogilner JG, et al. Leptin affects intestinal epithelial cell turnover in correlation with leptin receptor expression along the villus-crypt axis after massive small bowel resection in a rat[J]. Pediatr Res, 2009, 66(6): 648-653.
|
| 10 |
Sukhotnik I, Mogilner JG, Shteinberg D, et al. Leptin accelerates enterocyte turnover during methotrexate-induced intestinal mucositis in a rat[J]. Cancer Biol Ther, 2009, 8(10): 899-906.
|
| 11 |
Sukhotnik I, Helou H, Lurie M, et al. The effect of leptin on intestinal recovery following ischemia-reperfusion injury in a rat[J]. Pediatr Surg Int, 2007, 23(5): 473-478.
|
| 12 |
Gao J, Tian J, Lv Y, et al. Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/pathways in human endometrial cancer cells[J]. Cancer Sci, 2009, 100(3): 389-395.
|
| 13 |
Pérez-Pérez A, Maymó J, Duenas JL, et al. Leptin prevents apoptosis of trophoblastic cells by activation of MAPK pathway[J]. Arch Biochem Biophys, 2008, 477(2): 390-395.
|
| 14 |
Saxena NK, Sharma D, Ding X, et al. Concomitant activation of the JAK/STAT, PI3K/AKT, and ERK signaling is involved in leptin-mediated promotion of invasion and migration of hepatocellular carcinoma cells[J]. Cancer Res, 2007, 67(6): 2497-2507.
|
| 15 |
Buttar NS, Wang KK. Mechanisms of disease: carcinogenesis in barrett's esophagus[J]. Nat Clin Pract Gastroenterol Hepatol, 2004, 1(2): 106-112.
|
| 16 |
陈慧，杨冬梓，蔡卫斌, 等. Leptin对缺氧诱导胎肺Ⅱ型上皮细胞凋亡的影响及机制[J].中国病理生理杂志, 2007, 23(5): 959-963．
|
| 17 |
Pai R, Lin C, Tran T, et al. Leptin activates STAT and ERK2 pathways and induces gastric cancer cell proliferation[J]. Biochem Biophys Res Commun, 2005, 331(4): 984-992.
|
| 18 |
Rouet-Benzineb P, Aparicio T, Guilmeau S, et al. Leptin counteracts sodium butyrate-induced apoptosis in human colon cancer HT-29 cells via NF-kappaB signaling[J]. J Biol Chem, 2004, 279(16): 16495-16502.
|
| 19 |
Russo VC, Metaxas S, Kobayashi K, et al. Antiapoptotic effects of leptin in human neuroblastoma cells[J]. Endocrinology, 2004, 145(9): 4103-4112.
|
| 20 |
Rouet-Benzineb P, Aparicio T, Guilmeau S, et al. Leptin counteracts sodium butyrate-induced apoptosis in human colon cancer HT-29 cells via NF-kappaB signaling[J]. J Biol Chem, 2004, 279(16): 16495-16502．
|
| 21 |
周少丽，魏涧琦，李晓芸, 等. 瘦素对缺氧复氧LO2肝细胞凋亡及Fas/FasL表达的影响[J]. 中国病理生理杂志, 2009, 25(6): 1147-1150.
|
| 22 |
Nishi Y, Isomoto H, Uotani S, et al. Enhanced production of leptin in gastric fundic mucosa with Helicobacter pylori infection[J]. World J Gastroenterol, 2005, 11(5): 596-699.
|
| 23 |
Edward O, Adeyemi, Salim A, et al. Mechanisms of action of leptin in preventing gastric ulcer[J]. World J Gastroenterel, 2005, 11(27): 4154-4160.
|
| 24 |
王晓辉，王录焕，薛辉, 等. 瘦素对肠缺血再灌注损伤大鼠外周血TNF-a和IL-10表达及小肠局部病理损伤的影响[J]. 第二军医大学学报, 2008, 29(3): 250-253.
|
| 25 |
林季，颜光涛，王录焕, 等.肠缺血再灌注损伤对leptin蛋白质及mRNA水平的影响[J]. 中国危重病急救医学, 2004, 16(11): 651-655．
|
| 26 |
Claycombe K, King LE, Fraker PJ. A role for leptin in sustaining lymphopoiesis and myelopoiesis [J]. Proc Natl Acad Sci USA, 2008, 105(6): 2017-2021.
|
| 27 |
Hsu A, Aronoff DM, Phipps J, et al. Leptin improves pulmonary bacterial clearance and survival in ob/ob mice during pneumococcal pneumonia[J]. Clin Exp Immunol, 2007, 150(2): 332-339．
|
| 28 |
Santos-Alvarez J, Goberna R, Sanchez-Margalet V. Human leptin stimulates proliferation and activation of human circulating monocytes[J]. Cell Immunol, 1999, 194(1): 6-11.
|
| 29 |
Zarkesh-Esfahani H, Pockley AG, Wu Z, et al. Leptin indirectly activates human neutrophils via induction of TNF-alpha[J]. J lmmunol, 2004, 172(3): 1809-1814.
|
| 30 |
Papathanassoglou E, EbHasehimi K, Li XC, et al. Leptin receptor expression and signaling in lymphocytes: kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice[J]. J Immunol, 2006, 176(12): 7745-7752．
|
| 31 |
Batra A, Okur B, Erben U, et al. Leptin: a critical regulator of CD4+ T-cell polarization in vitro and in vivo[J]. Endocrinology, 2010, 151(1): 56-62.
|
| 32 |
Lam QL, Wanq S, Ko OK, et al. Leptin signaling maintains B-cell homeostasis via induction of Bcl-2 and Cyclin D1[J]. Proc Natl Acad Sci USA, 2010, 107(31): 13812-13817.
|
| 33 |
王晓辉，王录焕，邓子辉, 等. 瘦素对肠缺血/再灌注损伤大鼠肝脏功能的影响及其机制[J]. 感染、炎症、修复, 2007, 8(3): 137-139.
|
| 34 |
颜光涛，薛辉，林季, 等. 脓毒症后瘦素对肠道功能的影响及对肝肾功能的保护作用[J]. 中国病理生理杂志, 2007, 23(8): 1566-1569.
|
| 35 |
李维新，严祥. 胃瘦素的研究新进展[J]. 中华老年多器官疾病杂志, 2012, 11(4): 312-315.
|
| 36 |
Kiely JM, Noh JH, Svatek CL, et al. Altered small intestinal absorptive enzyme activities in leptin-deficient obese mice: influence of bowel resection[J]. J Pediatr Surg, 2006, 41(7): 1243-1249．
|
| 37 |
Yarandi SS, Hebbar G, Sauer CG, et al. Diverse roles of leptin in the gastrointestinal tract: modulation of motility, absorption, growth, and inflammation[J]. Nutrition, 2011, 27(3): 269-275.
|
| 38 |
Fanjul C, Barrenetxe J, Inigo C, et al. Leptin regulates sugar and amino acids transport in the human intestinal cell line Caco-2[J]. Acta Physiol (Oxf), 2012, 205(1): 82-91.
|