研究小型猪普通外科腹腔镜手术中不同气腹压力对循环功能的影响，以选择适宜的气腹压完成腹腔镜手术。

选择24只25~30 kg巴马小型猪，随机分为A、B、C、D共4组，分别以10、13、15、17 mmHg（1.330、1.729、1.995、2.261 kPa）的气腹压进行腹腔镜实验手术，于不同时间点对心率（HR）、平均动脉压（MAP）、动脉血液气体及酸碱分析指标进行监测。

A组的MAP无显著变化，B组在气腹建立30 min和180 min时显著升高，C、D组则在气腹建立30 min后呈显著降低趋势，各时间点的组间差异有统计学意义（P<0.01）；4组HR在气腹后均呈逐渐升高趋势，且气腹压力越大，影响越明显；气腹开始至60 min内，4组的氧分压（PaO₂）几乎无明显变化，120 min时A、C、D组降低（P<0.05）；二氧化碳分压（PaCO₂）在气腹后均有升高，血液酸碱度也随之降低，组间差异有统计学意义（P<0.01）。

在25~30 kg的小型猪普通外科腹腔镜手术模型中，既要保证手术视野，又要降低气腹对机体循环功能的影响，气腹压力的选择以10~13 mmHg为宜，不应超过15 mmHg。

To investigate the effects of different pneumoperitoneum pressures on circulatory function in miniature pigs during laparoscopic surgery, and to select appropriate pneumoperitoneum pressure to complete laparoscopic surgery.

A total of twenty-four Bama miniature pigs with 25-30 kg weight were randomly divided into 4 groups: group A, B, C and D. The pneumoperitoneum pressure of 10, 13, 15, 17 mmHg (1.330, 1.729, 1.995, 2.261 kPa) was used for laparoscopic operation, heart rate (HR), mean arterial pressure (MAP) and arterial blood gas were monitored at different time points.

In terms of MAP, there was no significant change in group A, but it increased significantly in group B at 30 min and 180 min, and decreased significantly in group C and D after 30 min of pneumoperitoneum (P<0.01). HR in the four groups increased gradually after pneumoperitoneum, and the greater the pneumoperitoneum pressure, the more obvious the impact. PaO₂ in the four groups had no significant changes from the beginning of pneumoperitoneum to 60 minutes, but decreased in group A, C and D at 120 minutes (P<0.05). PaCO₂ increased after pneumoperitoneum, and with the increasing of PaCO₂, blood acid-base value decreased. There were significant differences among the four groups (P<0.01).

In the general laparoscopic surgery, pneumoperitoneum can affect the circulatory function of 25-30 kg miniature pigs. The pneumoperitoneal pressure should be controlled in the range of 10-13 mmHg and should not exceed 15 mmHg, so as to ensure the operative field of vision and reduce the impact of pneumoperitoneum on the body.