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中华普通外科学文献(电子版) ›› 2024, Vol. 18 ›› Issue (02) : 151 -155. doi: 10.3877/cma.j.issn.1674-0793.2024.02.017

综述

肝移植术后早期肝功能不全的诊治及研究进展
宁江红1, 高彬1, 蒋铁民1,()   
  1. 1. 830054 乌鲁木齐,新疆医科大学第一附属医院消化血管外科中心肝胆包虫病外科
  • 收稿日期:2023-10-06 出版日期:2024-04-01
  • 通信作者: 蒋铁民
  • 基金资助:
    中央引导地方科技发展专项资金项目(ZYYD2022B06)新疆维吾尔自治区重点实验室开放课题基金项目(2021D04024)

Diagnosis, treatment and research progress of primary graft dysfunction after liver transplantation

Jianghong Ning1, Bin Gao1, Tiemin Jiang1,()   

  1. 1. Department of Hepatobiliary & Hydatid Disease, Digestive &Vascular Surgery Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
  • Received:2023-10-06 Published:2024-04-01
  • Corresponding author: Tiemin Jiang
引用本文:

宁江红, 高彬, 蒋铁民. 肝移植术后早期肝功能不全的诊治及研究进展[J/OL]. 中华普通外科学文献(电子版), 2024, 18(02): 151-155.

Jianghong Ning, Bin Gao, Tiemin Jiang. Diagnosis, treatment and research progress of primary graft dysfunction after liver transplantation[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2024, 18(02): 151-155.

肝移植是治疗终末期肝病的一种挽救生命性方法,术后往往会出现移植物早期功能不全(障碍)。早期肝功能不全已成为肝移植术后的一种严重并发症,直接影响患者的预后。本文通过对肝移植术后早期肝功能不全的诊断、病理生理、影响因素以及预测模型等进行综述,以期通过早期发现、诊断并处理干预影响其发生的因素,从而提升肝移植成功率,不断改善肝移植患者的生存预后。

Liver transplantation is a life-saving method for treating end-stage liver diseases,while primary graft dysfunction (PGD) often occurs after surgery.PGD has become a serious complication after liver transplantation, directly affecting the prognosis of patients.This article reviews the diagnosis,pathophysiology, influencing factors, and predictive models of PGD after liver transplantation, with the aim of early detection, diagnosis, and intervention to improve the success rate of liver transplantation and continuously improve the survival prognosis of liver transplant patients.

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