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中华普通外科学文献(电子版) ›› 2024, Vol. 18 ›› Issue (06) : 415 -420. doi: 10.3877/cma.j.issn.1674-0793.2024.06.003

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晚期肝内胆管癌系统性治疗研究进展
张森权1, 黄傲1, 周俭1,()   
  1. 1.200032 上海,复旦大学附属中山医院肝肿瘤外科复旦大学附属中山医院肝癌研究所 癌变与侵袭原理教育部重点实验室
  • 收稿日期:2024-05-22 出版日期:2024-12-01
  • 通信作者: 周俭

Systemic therapy research progress of intrahepatic cholangiocarcinoma

Senquan Zhang, Ao Huang, Jian Zhou()   

  • Received:2024-05-22 Published:2024-12-01
  • Corresponding author: Jian Zhou
引用本文:

张森权, 黄傲, 周俭. 晚期肝内胆管癌系统性治疗研究进展[J]. 中华普通外科学文献(电子版), 2024, 18(06): 415-420.

Senquan Zhang, Ao Huang, Jian Zhou. Systemic therapy research progress of intrahepatic cholangiocarcinoma[J]. Chinese Archives of General Surgery(Electronic Edition), 2024, 18(06): 415-420.

[1]
Brindley PJ, Bachini M, Ilyas SI, et al. Cholangiocarcinoma[J]. Nat Rev Dis Primers, 2021, 7(1): 65.
[2]
Moris D, Palta M, Kim C, et al. Advances in the treatment of intrahepatic cholangiocarcinoma: An overview of the current and future therapeutic landscape for clinicians[J]. CA Cancer J Clin,2023, 73(2): 198-222.
[3]
Shi GM, Huang XY, Wu D, et al. Toripalimab combined with lenvatinib and GEMOX is a promising regimen as first-line treatment for advanced intrahepatic cholangiocarcinoma: A singlecenter, single-arm, phase 2 study[J]. Signal Transduct Target Ther,2023, 8(1): 106.
[4]
Dong L, Lu D, Chen R, et al. Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma[J]. Cancer Cell, 2022, 40(1): 70-87.
[5]
Valle J, Wasan H, Palmer DH, et al. Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer[J]. N Engl J Med, 2010,362(14): 1273-1281.
[6]
Sasaki T, Isayama H, Nakai Y, et al. A randomized phase Ⅱ study of gemcitabine and S-1 combination therapy versus gemcitabine monotherapy for advanced biliary tract cancer[J]. Cancer Chemother Pharmacol, 2013, 71(4): 973-979.
[7]
Morizane C, Okusaka T, Mizusawa J, et al. Combination gemcitabine plus S-1 versus gemcitabine plus cisplatin for advanced/recurrent biliary tract cancer: the FUGA-BT (JCOG1113) randomized phaseⅢ clinical trial[J]. Ann Oncol, 2019, 30(12): 1950-1958.
[8]
Fiteni F, Nguyen T, Vernerey D, et al. Cisplatin/gemcitabine or oxaliplatin/gemcitabine in the treatment of advanced biliary tract cancer: A systematic review[J]. Cancer Med, 2014, 3(6): 1502-1511.
[9]
Phelip Jm, Desrame J, Edeline J, et al. Modified FOLFIRINOX versus CISGEM chemotherapy for patients with advanced biliary tract cancer (PRODIGE 38 AMEBICA): A randomized phase study[J]. J Clin Oncol, 2022, 40(3): 262-271.
[10]
Ioka T, Kanai M, Kobayashi S, et al. Randomized phase Ⅲ study of gemcitabine, cisplatin plus S-1 versus gemcitabine, cisplatin for advanced biliary tract cancer (KHBO1401-MITSUBA)[J]. J Hepatobiliary Pancreat Sci, 2023, 30(1): 102-110.
[11]
Shroff RT, Javle MM, Xiao LC, et al. Gemcitabine, cisplatin, and nab-paclitaxel for the treatment of advanced biliary tract cancers:A phase 2 clinical trial[J]. JAMA Oncol, 2019, 5(6): 824-830.
[12]
Abou-Alfa GK, Sahai V, Hollebecque A, et al. Pemigatinib for previously treated, locally advanced or metastatic cholangiocarcinoma: A multicentre, open-label, phase 2 study[J].Lancet Oncol, 2020, 21(5): 671-684.
[13]
Shi GM, Huang XY, Wen TF, et al. Pemigatinib in previously treated Chinese patients with locally advanced or metastatic cholangiocarcinoma carrying FGFR2 fusions or rearrangements: A phase Ⅱ study[J]. Cancer Med, 2023, 12(4): 4137-4146.
[14]
Javle M, Lowery M, Shroff RT, et al. Phase Ⅱ study of BGJ398 in patients with FGFR-altered advanced cholangiocarcinoma[J]. J Clin Oncol, 2018, 36(3): 276-282.
[15]
Goyal L, Meric-Bernstam F, Hollebecque A, et al. Futibatinib for FGFR2-rearranged intrahepatic cholangiocarcinoma[J]. N Engl J Med, 2023, 388(3): 228-239.
[16]
Lowery MA, Burris HA 3rd, Janku F, et al. Safety and activity of ivosidenib in patients with IDH1-mutant advanced cholangiocarcinoma: A phase 1 study[J]. Lancet Gastroenterol Hepatol, 2019, 4(9): 711-720.
[17]
Abou-Alfa GK, Macarulla T, Javle MM, et al. Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarlDHy):A multicentre, randomised, double-blind, placebo-controlled,phase 3 study[J]. Lancet Oncol, 2020, 21(6): 796-807.
[18]
Chakrabarti S, Kamgar M, Mahipal A. Targeted therapies in advanced biliary tract cancer: An evolving paradigm[J]. Cancers(Basel), 2020, 12(8): 2039.
[19]
Subbiah V, Lassen U, Elez E, et al. Dabrafenib plus trametinib in patients with BRAFV600E-mutated biliary tract cancer (ROAR):A phase 2, open-label, single-arm, multicentre basket trial[J].Lancet Oncol, 2020, 21(9): 1234-1243.
[20]
Wang Z, Strasser A, Kelly GL. Should mutant TP53 be targeted for cancer therapy?[J]. Cell Death Differ, 2022, 29(5): 911-920.
[21]
LoRusso P, Yamamoto N, Patel MR, et al. The MDM2-p53 antagonist brigimadlin (BI 907828) in patients with advanced or metastatic solid tumors: results of a phase a, first-in-human,dose-escalation study[J]. Cancer Discov, 2023, 13(8): 1802-1813.
[22]
Zhang R, Cui Y, Guan X, et al. A recombinant human adenovirus type 5 (H101) combined with chemotherapy for advanced gastric carcinoma: A retrospective cohort study[J]. Front Oncol, 2021, 11:752504.
[23]
Ou SI, Janne PA, Leal TA, et al. First-in-human phase / B dosefinding study of adagrasib (MRTX849) in patients with advanced KRAS(G12C) solid tumors (KRYSTAL-1)[J]. J Clin Oncol, 2022,40(23): 2530-2538.
[24]
Pan TT, Wang W, Jia WD, et al. A single-center experience of sorafenib monotherapy in patients with advanced intrahepatic cholangiocarcinoma[J]. Oncol Lett, 2017, 13(5): 2957-2964.
[25]
El-Khoueiry AB, Rankin CJ, Ben-Josef E, et al. SWOG 0514:A phase study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma[J].Invest New Drugs, 2012, 30(4): 1646-1651.
[26]
Ueno M, Ikeda M, Sasaki T, et al. Phase 2 study of lenvatinib monotherapy as second-line treatment in unresectable biliary tract cancer: primary analysis results[J]. BMC Cancer, 2020, 20(1):1105.
[27]
Piha-Paul SA, Oh DY, Ueno M, et al. Efficacy and safety of pembrolizumab for the treatment of advanced biliary cancer:results from the KEYNOTE-158 and KEYNOTE-028 studies[J].Int J Cancer, 2020, 147(8): 2190-2198.
[28]
Doki Y, Ueno M, Hsu CH, et al. Tolerability and efficacy of durvalumab, either as monotherapy or in combination with tremelimumab, in patients from Asia with advanced biliary tract,esophageal, or head-and-neck cancer[J]. Cancer Med, 2022,11(13): 2550-2560.
[29]
Kim RD, Chung V, Alese OB, et al. A phase 2 multi-institutional study of nivolumab for patients with advanced refractory biliary tract cancer[J]. JAMA Oncol, 2020, 6(6): 888-894.
[30]
Kelley RK, Ueno M, Yoo C, et al. Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliarytract cancer(KEYNOTE-966): A randomised, double-blind, placebocontrolled, phase 3 trial[J]. Lancet, 2023, 401(10391): 1853-1865.
[31]
Le DT, Durham JN, Smith KN, et al. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade[J]. Science,2017, 357(6349): 409-413.
[32]
Martin RCG 2nd, Simo KA, Hansen P, et al. Drug-eluting bead,irinotecan therapy of unresectable intrahepatic cholangiocarcinoma(DELTIC) with concomitant systemic gemcitabine and cisplatin[J].Ann Surg Oncol, 2022, 29(9): 5462-5473.
[33]
Buettner S, Braat AJAT, Margonis GA, et al. Yttrium-90 radioembolization in intrahepatic cholangiocarcinoma: A multicenter retrospective analysis[J]. J Vasc Interv Radiol, 2020,31(7): 1035-1043.
[34]
Edeline J, Touchefeu Y, Guiu B, et al. Radioembolization plus chemotherapy for first-line treatment of locally advanced intrahepatic cholangiocarcinoma: A phase 2 clinical trial[J]. JAMA Oncol, 2020, 6(1): 51-59.
[35]
Cercek A, Boerner T, Tan BR, et al. Assessment of hepatic arterial infusion of floxuridine in combination with systemic gemcitabine and oxaliplatin in patients with unresectable intrahepatic cholangiocarcinoma: A phase 2 clinical trial[J]. JAMA Oncol,2020, 6(1): 60-67.
[36]
Franssen S, Soares KC, Jolissaint JS, et al. Comparison of hepatic arterial infusion pump chemotherapy vs resection for patients with multifocal intrahepatic cholangiocarcinoma[J]. JAMA Surg, 2022,157(7): 590-596.
[37]
Kim GH, Kim PH, Kim JH, et al. Thermal ablation in the treatment of intrahepatic cholangiocarcinoma: A systematic review and metaanalysis[J]. Eur Radiol, 2022, 32(2): 1205-1215.
[38]
Zhang SJ, Hu P, Wang N, et al. Thermal ablation versus repeated hepatic resection for recurrent intrahepatic cholangiocarcinoma[J].Ann Surg Oncol, 2013, 20(11): 3596-3602.
[39]
Tao R, Krishnan S, Bhosale PR, et al. Ablative radiotherapy doses lead to a substantial prolongation of survival in patients with inoperable intrahepatic cholangiocarcinoma: A retrospective dose response analysis[J]. J Clin Oncol, 2016, 34(3): U219-U268.
[40]
Hong TS, Wo JY, Yeap BY, et al. Multi-institutional phase Ⅱ study of high-dose hypofractionated proton beam therapy in patients with localized, unresectable hepatocellular carcinoma and intrahepatic cholangiocarcinoma[J]. J Clin Oncol, 2016, 34(5): 460-468.
[41]
Sapisochin G, Ivanics T, Heimbach J. Liver transplantation for intrahepatic cholangiocarcinoma: ready for prime time?[J].Hepatology, 2022, 75(2): 455-472.
[42]
Lunsford KE, Javle M, Heyne K, et al. Liver transplantation for locally advanced intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: A prospective case-series[J]. Lancet Gastroenterol Hepatol, 2018, 3(5): 337-348.
[43]
McMillan RR, Javle M, Kodali S, et al. Survival following liver transplantation for locally advanced, unresectable intrahepatic cholangiocarcinoma[J]. Am J Transplant, 2022, 22(3): 823-832.
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