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中华普通外科学文献(电子版) ›› 2010, Vol. 04 ›› Issue (05) : 471 -474. doi: 10.3877/cma.j.issn.1674-0793.2010.05.020

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论著

LigasureTM血管闭合系统在胃癌根治术中的疗效评价
杨斌1, 周军1, 陈双1,(), 赖东明1, 张育超1, 江志鹏1, 褚忠华1   
  1. 1. 510120 广州,中山大学附属第二医院胃肠胰外科
  • 收稿日期:2010-03-22 出版日期:2010-10-01
  • 通信作者: 陈双

Randomized clinical trial of LigasureTM versus conventional surgery in radical resection of gastric carcinoma

Bin YANG1, Jun ZHOU1, Shuang CHEN1,(), Dong-ming LAI1, Yu-chao ZHANG1, Zhi-peng JIANG1, Zhong-hua CHU1   

  1. 1. Department of Gastrointestinal Surgery, the Second Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510120, China
  • Received:2010-03-22 Published:2010-10-01
  • Corresponding author: Shuang CHEN
  • About author:
    Corresponding author: CHEN Shuang, Email:
引用本文:

杨斌, 周军, 陈双, 赖东明, 张育超, 江志鹏, 褚忠华. LigasureTM血管闭合系统在胃癌根治术中的疗效评价[J/OL]. 中华普通外科学文献(电子版), 2010, 04(05): 471-474.

Bin YANG, Jun ZHOU, Shuang CHEN, Dong-ming LAI, Yu-chao ZHANG, Zhi-peng JIANG, Zhong-hua CHU. Randomized clinical trial of LigasureTM versus conventional surgery in radical resection of gastric carcinoma[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2010, 04(05): 471-474.

目的

比较LigasureTM血管闭合系统和传统结扎方法在开放式胃癌D2根治术中应用的安全性和疗效。

方法

2006年6月至2008年12月间行胃癌D2根治术86例患者,随机分为LigasureTM组(45例)和传统手术组(41例),比较两组患者的手术时间、术中出血量、术后疗效及并发症等临床资料。

结果

两组均无手术死亡,LigasureTM组手术时间、术中出血量显著低于常规手术组(P<0.05),术后平均淋巴结检出数、并发症发生率、肛门排气时间、术后住院日无统计学差异。LigasureTM组术后第1天腹腔引流液少于常规手术组(P<0.05),第2~5天及术后总量两组无统计学差异。

结论

LigasureTM血管闭合系统在胃癌D2根治术中安全可靠,与传统结扎手术相比术中出血减少,手术时间缩短,具良好的临床应用价值。

Objective

To evaluate the the efficacy and safety of LigasureTM Vessel Sealing System and conventional clamping method in gastric D2 lymphadenectomy.

Methods

Patients undergoing gastric D2 lymphadenectomy were randomly divided into two groups treated with LigasureTM(n=45) and conventional method (n=41), Operation time, intraoperative blood loss, postoperative courses and complications were analyzed prospectively.

Results

There were no hospital deaths. The operation time, intraoperative blood loss in LigasureTM group were significantly less than that in conventional operation (P<0.05). No significant differences were found between the two groups in number of lymph node removed, postoperative complications, time to pass flatus and hospital stay. The volume of intraperitoneal drainage in LigasureTM group were less than those in conventional group at the first day (P<0.05), but there was no significant difference from the 2nd to the 5th day after operation.

Conclusion

The LigasureTM Vessel Sealing System is safe and effective for use in gastric D2 lymphadenectomy, and is associated with a shorter operation time and decreased blood loss compared with conventional surgery.

表1 86例胃癌患者的临床资料(例)
表2 两组患者围术期情况比较(±s
表3 两组患者术后1~5 d腹腔引流液量[±s(ml)]
1
Lee WJ,Chen TC,Lai IR, et al. Randomized clinical trial of Ligasure versus conventional surgery for extended gastric cancer resection. Br J Surg, 2003, 90(12): 1493-1496.
2
Romano F,Caprotti R,Franciosi C, et al. Laparoscopic splenectomy using Ligasure. Preliminary experience. Surg Endosc, 2002, 16(11): 1608-1611.
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Horgan PG. A novel technique for parenchymal division during hepatectomy. Am J Surg, 2001, 181(3): 2362-2366.
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Japanese Research Society for Gastric Cancer. The General Rules for Gastric Cancer Research(13th edn). Kanehara: Tokyo, 1999.
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Gelmini R,Colombo G,Quaranta N, et al. Sutureless and stapleless laparoscopic splenectomy using radiofrequency:Ligasure device. Surg Endosc, 2006, 20(6): 991-994.
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Carbonell AM,Joels CS,Kercher KW, et al. A comparison of laparoscopic bipolar vessel sealing devices in the hemostasis of small-, medium-, and large-sized arteries. J Laparoendosc Adv Surg Tech A, 2003, 13(6): 377-380.
7
Matthews BD,Pratt BL,Backus CL, et al. Effectiveness of the ultrasonic coagulating shears, Ligasure vessel sealer, and surgical clipapplication in biliary surgery: a comparative analysis. Am Surg, 2001, 67(9): 901-906.
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