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中华普通外科学文献(电子版)

中华普通外科学文献(电子版) ›› 2011, Vol. 05 ›› Issue (02) : 100 -103. doi: 10.3877/cma.j.issn.1674-0793.2011.02.004

所属专题： 文献；

论著

高血流动力对大隐静脉和脾静脉血管重塑的影响
褚海波1,†(), 边小维2, 徐永波1, 王涛3, 郭文君2   
  1. 1. 261021　潍坊，解放军第89医院普外中心
    2. 潍坊医学院
    3. 261021　潍坊，解放军第89医院病理科
  • 收稿日期:2010-09-13 出版日期:2011-04-01
  • 通信作者: 褚海波

Effects of saphenous vein and splenic vein in vascular remodeling by high hemodynamics

Hai-bo CHU1,†(), Xiao-wei BIAN2, Yong-bo XU1, Tao WANG3, Wen-jun GUO2   

  1. 1. Center of General Surgery, The 89th Hospital of PLA, Weifang 261021, China
  • Received:2010-09-13 Published:2011-04-01
  • Corresponding author: Hai-bo CHU
  • About author:
    Corresponding author: CHU Hai-bo, Email:
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褚海波, 边小维, 徐永波, 王涛, 郭文君. 高血流动力对大隐静脉和脾静脉血管重塑的影响[J]. 中华普通外科学文献(电子版), 2011, 05(02): 100-103.

Hai-bo CHU, Xiao-wei BIAN, Yong-bo XU, Tao WANG, Wen-jun GUO. Effects of saphenous vein and splenic vein in vascular remodeling by high hemodynamics[J]. Chinese Archives of General Surgery(Electronic Edition), 2011, 05(02): 100-103.

目的

探讨高血流动力对大隐静脉和脾静脉血管重塑的影响。

方法

收集曲张大隐静脉和门静脉高压性脾静脉管壁标本34例，设正常大隐静脉和脾静脉14例为对照组，光学显微镜下观察HE染色和Masson染色后的大隐静脉、脾静脉管壁组织学改变。

结果

HE染色曲张大隐静脉管壁呈不均匀性增厚改变，高压性脾静脉呈均匀性增厚改变；Masson染色管壁增厚，以内膜、中膜肌层和纤维结缔组织增生为主，曲张的大隐静脉（2/20）内膜轻度黏液样变性，高压性脾静脉（5/14）重度黏液性变性。

结论

高血流动力学影响大隐静脉和脾静脉管壁的重塑，提示内脏静脉比外周静脉病理改变更明显。

关键词: 大隐静脉, 脾静脉, 血流动力学, 血管重塑
Objective

To study the effects of saphenous vein and splenic vein in vascular remodeling with high hemodynamic.

Methods

Thirty-four cases were collected from the samples of great saphenous varicose vein and splenic vein with portal hypertension and 14 cases from normal great saphenous vein and splenic vein as the control group. The histological changes of cases with HE and Masson staining were observed by the light microscope.

Results

With HE staining the wall thickening of the varicose great saphenous vein was uneven and splenic vein was high uniformity. With Masson staining the wall thickening was mainly with endometrial muscularis, membrane muscularis and fibrous connective tissue hyperplasia. The mucinousdegeneration of varicose saphenous vein was less and splenic vein was heavier after Masson staining.

Conclusions

The effects of saphenous vein and splenic vein in vascular remodeling with high hemodynamic suggest that pathological changes in the visceral vein were more obvious than the peripheral vein.

Key words: Saphenous vein, Splenic vein, Hemodynamics, Vascular remodeling
图1 曲张大隐静脉管壁增厚不均匀，内膜、中膜分界清晰（HE×100）
图2 病理脾静脉管壁增厚较均匀，内膜、中膜分界不清（HE×100）
图3 曲张大隐静脉管壁胶原纤维大量增生、不规则（Masson×40）
图4 曲张大隐静脉管壁平滑肌束增生不均匀（Masson×100）
图5 病理脾静脉管壁胶原纤维大量增生，内膜可见黏液样变性（Masson×100）
图6 病理脾静脉管壁平滑肌束增生较均匀（Masson×200）
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