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中华普通外科学文献(电子版) ›› 2013, Vol. 07 ›› Issue (06) : 496 -500. doi: 10.3877/cma.j.issn.1674-0793.2013.06.019

所属专题: 文献

综述

立体定向放射消融治疗肝胰肿瘤的临床应用进展
王振宇1, 张群1, 文碧秀1   
  1. 1. 510080 广州,中山大学附属第一医院放射治疗科
  • 收稿日期:2013-04-09 出版日期:2013-12-01

Advance and clinical application of stereotactic ablative radiotherapy in liver and pancreatic cacinoma

Zhen-yu WANG1, Qun ZHANG1, Bi-xiu WEN1   

  1. 1. Department of Radiation Oncology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
  • Received:2013-04-09 Published:2013-12-01
引用本文:

王振宇, 张群, 文碧秀. 立体定向放射消融治疗肝胰肿瘤的临床应用进展[J/OL]. 中华普通外科学文献(电子版), 2013, 07(06): 496-500.

Zhen-yu WANG, Qun ZHANG, Bi-xiu WEN. Advance and clinical application of stereotactic ablative radiotherapy in liver and pancreatic cacinoma[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2013, 07(06): 496-500.

立体定向放射消融(SABR)是一种对肿瘤靶区采用单次或几次大剂量的精确照射,使肿瘤靶区形成放射性毁损,而靶区外正常组织受照剂量很小的治疗手段。目前该技术治疗不能手术的原发性肝细胞癌、早期非小细胞肺癌等取得了较好的疗效,并越来越多地被应用于腹部肿瘤临床。本文就立体定向放射消融在肝胰肿瘤的临床应用及其在放射物理生物学方面的进展做一综述。

Stereotactic ablative radiotherapy (SABR) is a special type of radiation therapy to deliver a high dose of radiation to the extracranial tumor in one or a small number of fractions with a high degree of precision. The tumor target is destroyed by ionizing irradiation while minimizing the exposure of radiation to normal tissues. SABR has been applied to treat patients with medically inoperable primary hepatocellular carcinoma, non-small-cell lung cancer and so on with promising effect. This article has comprehensively reviewed the clinical application of SABR in liver and pancreatic cancer and the progress in radiophysics and radiobiology of SABR.

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