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中华普通外科学文献(电子版) ›› 2022, Vol. 16 ›› Issue (04) : 273 -277. doi: 10.3877/cma.j.issn.1674-0793.2022.04.003

论著

三维可视化技术结合术中超声在可切除肝癌腹腔镜手术的应用
徐耀博1, 吴斌全1,()   
  1. 1. 233000 蚌埠医学院第一附属医院肝胆外科
  • 收稿日期:2022-05-26 出版日期:2022-08-01
  • 通信作者: 吴斌全
  • 基金资助:
    安徽省自然科学基金项目(2008085J37); 安徽省高校自然科学基金项目(KJ2021A0731)

Application of three-dimensional visualization combined with intraoperative ultrasound in laparoscopic surgery for resectable primary liver cancer

Yaobo Xu1, Binquan Wu1,()   

  1. 1. Department of Hepatobiliary Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu 233000, China
  • Received:2022-05-26 Published:2022-08-01
  • Corresponding author: Binquan Wu
引用本文:

徐耀博, 吴斌全. 三维可视化技术结合术中超声在可切除肝癌腹腔镜手术的应用[J/OL]. 中华普通外科学文献(电子版), 2022, 16(04): 273-277.

Yaobo Xu, Binquan Wu. Application of three-dimensional visualization combined with intraoperative ultrasound in laparoscopic surgery for resectable primary liver cancer[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2022, 16(04): 273-277.

目的

探讨术前应用三维可视化技术结合术中超声实时引导在可切除原发性肝癌腹腔镜手术中应用的近期效果及价值。

方法

回顾性分析蚌埠医学院第一附属医院2021年1月至2022年3月行腹腔镜肝切除术的68例原发性肝癌患者资料,根据术前是否行肝脏三维重建及术中超声引导,将患者分为对照组和观察组,各34例。对照组术前增强CT检查后行手术规划,观察组术前在增强CT的基础上采用三维可视化技术进行肝脏三维重建,拟定手术方案,术中行超声实时引导。对比两组患者的手术方式、术中出血量、术中输血比例、肝门阻断时间、手术时间、术后并发症发生率及术后住院时间。

结果

与对照组相比,观察组患者术中出血量更少,术中输血比例更低,术中肝门阻断时间、手术时间及术后住院时间更短(均P<0.05)。对照组6例患者中转开腹,两组手术方式比较差异有统计学意义(χ2=4.570,P=0.033)。观察组术后总并发症发生率显著低于对照组(11.8% vs 35.3%,χ2=5.231,P=0.022)。

结论

术前三维可视化技术结合术中超声引导在可切除原发性肝癌腹腔镜手术中的应用,有助于制定个体化手术策略,提升临床治疗效果,减少术中出血和肝门阻断时间,降低术后并发症的发生率,对腹腔镜肝切除手术的发展有重要指导意义。

Objective

To explore the short-term effect and value of preoperative three-dimensional visualization technology combined with intraoperative ultrasound real-time guidance in laparoscopic surgery for resectable primary liver cancer.

Methods

A total of 68 patients with resectable primary liver cancer undergoing laparoscopic hepatectomy in the First Affiliated Hospital of Bengbu Medical College from January 2021 to March 2022 were retrospectively analyzed. According to whether three-dimensional liver reconstruction before operation and intraoperative ultrasound guidance were performed, the patients were divided into the control group (traditional surgical planning after enhanced CT examination) and the observation group (three-dimensional liver reconstruction on the basis of enhanced CT combined with intraoperative ultrasound guidance), with 34 cases in each group. The method of operation, intraoperative blood loss, intraoperative blood transfusion, time of hepatic port blocking, operation time, the incidence of postoperative complications and postoperative hospital stay were observed and compared between the two groups.

Results

Compared with the control group, the patients in the observation group had less intraoperative blood loss, lower proportion of blood transfusion, and shorter intraoperative hepatic port blocking time, operation time and postoperative hospital stay (all P<0.05). Six patients in the control group were converted to open surgery, and the difference between the two groups was statistically significant (χ2=4.570, P=0.033). The incidence of postoperative complications in the observation group was significantly lower than that in the control group (11.8% vs 35.3%, χ2=5.231, P=0.022).

Conclusions

The application of preoperative three-dimensional visualization technique combined with intraoperative ultrasound guidance in laparoscopic resection of primary liver cancer helps to formulate individualized surgery strategies, to improve clinical treatment effects by shortening hepatic port blocking time and reducing intraoperative bleeding and the incidence of postoperative complications. It has important guiding significance for the development of laparoscopic hepatectomy.

表1 两组原发性肝癌患者一般资料
图1 术前CT及三维重建图片
图2 术中超声引导图片
表2 两组原发性肝癌患者围手术期相关指标
表3 两组患者腹腔镜肝切除术后并发症情况比较[例(%)]
[1]
Yang JD, Hainaut P, Gores GJ, et al. A global view of hepatocellular carcinoma: trends, risk, prevention and management[J]. Nat Rev Gastroenterol Hepatol, 2019, 16(10): 589-604.
[2]
Chan LK, Tsui YM, Ho DW, et al. Cellular heterogeneity and plasticity in liver cancer[J]. Semin Cancer Biol, 2022, 82: 134-149.
[3]
Fang C, Zhang P, Qi X. Digital and intelligent liver surgery in the new era: prospects and dilemmas[J]. EBioMedicine, 2019, 41: 693-701.
[4]
Xiangfei M, Yinzhe X, Yingwei P, et al. Open versus laparoscopic hepatic resection for hepatocellular carcinoma: A systematic review and meta-analysis[J]. Surg Endosc, 2019, 33(8): 2396-2418.
[5]
Ciria R, Cherqui D, Geller DA, et al. Comparative short-term benefits of laparoscopic liver resection: 9 000 cases and climbing [J]. Ann Surg, 2016, 263(4): 761-777.
[6]
中华医学会数字医学分会, 中国医师协会肝癌专业委员会, 中国医师协会临床精准医学专业委员会, 等. 复杂性肝脏肿瘤三维可视化精准诊治指南(2019版)[J]. 中国实用外科杂志, 2019, 39(8): 766-774.
[7]
雷鹏, 谢晓东, 唐超峰, 等. 三维可视化及3D打印技术在复杂肝脏肿瘤切除术中的应用[J/CD]. 中华肝脏外科手术学电子杂志, 2021,10(4): 371-375.
[8]
权冰, 李镇利, 韩骏, 等. 三维可视化技术在肝细胞癌切除术中的应用及展望[J/CD]. 中华肝脏外科手术学电子杂志,2019, 8(1): 18-21.
[9]
宋铎, 孙铎, 姜德帅. 三维可视化技术与二维影像技术在肝癌患者肝切除术中的疗效比较研究[J]. 临床和实验医学杂志, 2020, 19(6): 656-660.
[10]
Zhao D, Lau WY, Zhou W, et al. Impact of three-dimensional visualization technology on surgical strategies in complex hepatic cancer[J]. Biosci Trends, 2018, 12(5): 476-483.
[11]
Hu M, Hu H, Cai W, et al. The safety and feasibility of three-dimensional visualization technology assisted right posterior lobe allied with part of Ⅴ and Ⅷ sectionectomy for right hepatic malignancy therapy[J]. J Laparoendosc Adv Surg Tech A, 2018, 28(5): 586-594.
[12]
国家卫生健康委员会. 原发性肝癌诊疗指南(2022年版)[J/CD]. 中华普通外科学文献(电子版), 2022, 16(2): 81-96.
[13]
方驰华, 陈青山, 方程, 等. 三维可视化技术辅助的肝切除术治疗原发性肝癌的疗效分析[J]. 中华外科杂志, 2015, 53(8): 574-579.
[14]
中国肝胆外科术中超声学院. 腹腔镜超声在肝脏外科的应用专家共识(2017)[J]. 临床肝胆病杂志, 2018, 34(3): 486-493.
[15]
Kamiyama T, Kakisaka T, Orimo T. Current role of intraoperative ultrasonography in hepatectomy[J]. Surg Today, 2021, 51(12): 1887-1896.
[16]
Soliman HO, Gad ZS, Mahmoud AM, et al. Laparoscopy with laparoscopic ultrasound for pretreatment staging of hepatic focal lesions: A prospective study[J]. J Egypt Natl Canc Inst, 2011, 23(4): 141-145.
[17]
王伟, 胡娟英, 许明辉, 等. 肝脏三维重建术前规划结合术中超声引导在腹腔镜精准肝段切除的临床效果[J]. 浙江创伤外科, 2021, 26(2): 221-222.
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