对比真空辅助活检与传统开放活检技术在早期乳腺癌患者临床应用的可行性。

回顾性分析武警海南总队医院2008年1月至2012年6月间经病理组织学检查确诊的94例乳腺癌患者，分为超声或钼靶引导下行真空辅助旋切活检组（观察组）和传统开放手术活检组（对照组），比较两组患者手术时间、手术切口长度、术中出血量、患者满意率及术后保乳率、以及3年局部复发和远处转移率。

观察组活检手术时间、术中切口长度、术中出血量均明显少于对照组，差异有统计学意义（P<0.05）。术后观察组的满意度为98.8%，对照组为84.5%，观察组明显优于对照组。观察组活检术后行保乳手术的患者明显多于对照组，差异有统计学意义（30.2% vs 12.2%, χ²=4.314, P<0.05）。患者术后随访3年，局部复发率和远处转移率比较差异无统计学意义。

对早期乳腺癌患者，超声和钼靶引导下的乳腺微创旋切活检术具有耗时短、创伤小等优势，3年局部复发和远处转移与手术开放活检术相当，但尚需进一步延长观察时间明确。

To compare the advantages and disadvantages for vacuum assisted biopsy technique and the traditional open biopsy technology to further clarify the feasibility of clinical applica-tion.

A retrospective investigation was made for 94 breast cancer patients who were confirmed by pathological examination at Hainan Armed Police Corps Hospital from January 2008 to June 2012. The patients were divided into two groups, vacuum assisted biopsy group (observation group) and traditional open surgical biopsy group (control group). Operation time, length of incision, intraoperative bleeding vol-ume, patients satisfaction rate and postoperative patients treated with breast conserving rate, and 3-year local recurrence and distant metastasis rate comparison were compared.

Operative time, incision length, and blood loss of the observation group were significantly less than that of the control group (P<0.05). After the surgery, the satisfaction rate of the observation group was 98.8% and the control group was 84.5%, the observation group was significantly better than the control group. The patients with breast con-serving surgery in the observation group were significantly more than those in the control group (30.2% vs 12.2%, χ²=4.314, P<0.05). Patients were followed up for 3 years after surgery, and the 3-year local recur-rence rate and distant metastasis rate were not statistically different.

Vacuum assisted breast biopsy guided by ultrasound and mammography has the advantages of minimally invasive and short-er time. The 3-year local recurrence rate and distant metastasis rate are not statistically different com-pared with the traditional open surgical biopsy, but it still needs time for further clarification.