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中华普通外科学文献(电子版) ›› 2017, Vol. 11 ›› Issue (01) : 23 -27. doi: 10.3877/cma.j.issn.1674-0793.2017.01.006

所属专题: 文献

论著

小于2 cm的肝脏肿块的影像学诊断比较分析
王健1, 张万广1,()   
  1. 1. 430030 武汉,华中科技大学同济医学院附属同济医院肝脏外科中心
  • 收稿日期:2016-05-18 出版日期:2017-02-01
  • 通信作者: 张万广

Optimization of imaging diagnosis for hepatic lesions less than 2 cm

Jian Wang1, Wanguang Zhang1,()   

  1. 1. Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
  • Received:2016-05-18 Published:2017-02-01
  • Corresponding author: Wanguang Zhang
  • About author:
    Corresponding author: Zhang Wanguang, Email:
引用本文:

王健, 张万广. 小于2 cm的肝脏肿块的影像学诊断比较分析[J/OL]. 中华普通外科学文献(电子版), 2017, 11(01): 23-27.

Jian Wang, Wanguang Zhang. Optimization of imaging diagnosis for hepatic lesions less than 2 cm[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2017, 11(01): 23-27.

目的

评价超声、多层螺旋CT、磁共振影像学检查在小于2 cm肝脏肿块诊断中的价值。

方法

回顾性分析2010年1月至2012年1月在华中科技大学同济医学院附属同济医院肝脏外科中心就诊的53例资料完整的肝脏肿块患者临床资料,分别进行超声造影、多层螺旋CT增强、磁共振(PWI+DWI)检查,结合临床特征得出相应的初步诊断,再与病理和随访结果比较,分析三种影像学诊断的敏感度、特异度、准确性。

结果

病理和随访证实27例为原发性肝癌,10例肝脏局造型结节增生,9例肝血管瘤,4例转移性瘤,2例肝脏血管平滑肌脂肪瘤,1例囊肿混合感染。肝脏的PWI+DWI在诊断中表现出较高的敏感度、特异度和准确性(91%、97%、93%),稍优于超声造影,明显优于增强CT (P<0.05)。

结论

肝脏PWI+DWI和超声造影在小于2 cm肝脏肿块诊断中具有较高价值。

Objective

To evaluate the value of diagnosis for less than 2 cm liver lesions using contrast-enhanced ultrasound, contrast-enhanced computed tomography, enhanced perfusion imaging and diffusion imaging.

Methods

Fifty-three patients with nodules less than 2 cm underwent standardized contrast-enhanced ultrasound, CT, and MRI scans, respectively. Final diagnosis was determined by pathology or follow-up. Comparative analysis of its diagnostic sensitivity, specificity and accuracy was performed retrospectively.

Results

Based on the pathology or follow-up for patients, we confirmed that there were 27 patients of primary liver cancer, 10 focal nodular hyperplasia, 9 hemangioma, 4 metastatic tumor, 2 liver angioleiomyolipoma, and 1 liver cyst coincidence with infection. Combined with the three diagnosis tests, we found that enhanced perfusion imaging and diffusion imaging had a higher sensitivity, specifity and accuracy (91%, 97%, 93%, respectively) than contrast-enhanced ultrasound, and was significantly prior to computed tomography (P<0.05).

Conclusion

MR enhanced perfusion imaging and diffusion imaging and contrast-enhanced ultrasound has an excellent diagnostic value for liver tumors <2 cm.

图1 肝脏肿块超声造影结果(箭头所示为肿块位置) A为肝脏PWI+DWI显示良性病病变,经手术后病理诊断为肝脏局造性结节增生;B为肝脏超声造影诊断肝脏良性病变,不除外其他肿瘤性病变
图2 肝脏肿块增强CT结果(箭头所示肿块位置) A为肝脏增强CT提示肝脏肿瘤性病变,多考虑恶性可能;B为肝脏PWI+DWI考虑肝癌,经手术病理诊断确诊为肝细胞癌
图3 A为肝脏增强CT显示肝脏局灶性增生小结节;B为肝脏PWI+DWI提示肝脏不典型增生小结节。患者脾功能亢进,术中发现肝脏肿瘤性病变,病理报告:肝脏胆管混合细胞癌,箭头所示为肿块位置
表1 三种影像学检查在< 2 cm肝脏肿块诊断中的价值(64例)
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