探讨腹腔高压水囊叠加加压法液体模型的建立方法，以及压力-容积曲线变化规律。

以实验兔为研究对象，在腹腔内置入5个常规水囊（150 ml）及1个加压水囊，将0.9%氯化钠溶液注入加压水囊制作腹腔高压动物模型。每注入50 ml溶液，测压1次并记录。绘制腹腔内压（IAP）随0.9%氯化钠溶液量增加而升高的曲线图，应用简单线性回归分析方法分析腹腔内溶液增加量与腹腔压上升的关系。

在无张力关腹后，腹腔0.9%氯化钠溶液总量为750 ml，腹腔压力为0 cmH₂O（0 mmHg），之后随着0.9%氯化钠溶液的注入，腹腔压力缓慢增加，在溶液总量达900 ml后腹腔压力为8 cmH₂O（5.88 mmHg，0.784 kPa），之后腹腔压力明显上升，950 ml时为15 cmH₂O（11.03 mmHg，1.47 kPa），1 000 ml时为28 cmH₂O（20.59 mmHg，2.744 kPa），1 050 ml时为55 cmH₂O（40.44 mmHg，5.39 kPa）。腹腔压力与腹腔增容量存在函数关系：Y=0.164 2X-132（r=0.896，t=4.504，P=0.006）。

改良水囊叠加加压法可成功制作腹腔高压液体动物模型，腹腔压力-容积曲线表现为随着腹内0.9%氯化钠溶液增加而逐渐递增的单向曲线，在超过代偿临界点后，少量腹内液体增加即可引起腹腔压显著升高，升高速率呈现持续增长趋势。

To investigate the establishment of intra-abdominal hypertension in rabbit model of liquid water sac, and the change rule of pressure-volume curve.

Experimental rabbits were taken as research object, five conventional water sacs (150 ml) and one pressurized water sacs were placed in the abdominal cavity. Animal model of intra-abdominal hypertension was established with injection of 0.9% sodium chloride solution (NS) into pressurized water sac. Intra-abdominal pressure (IAP) was measured and recorded after each injection of 50 ml solution. The relationship between the increase volume of intra-peritoneal solution and abdominal pressure was analyzed by drawing pressure volume curve and simple linear regression method.

After tension-free abdominal surgery, the total volume of peritoneal NS solution was 750 ml, and the initial abdominal pressure was 0 cmH₂O. With the injection of NS solution, abdominal pressure increased slowly until the total volume reached 900 ml, and abdominal pressure was 8 cmH₂O (5.88 mmHg, 0.784 kPa). Then abdominal pressure was increased significantly followed by15 cmH₂O (11.03 mmHg, 1.47 kPa) at 950 ml, 28 cmH₂O (20.59 mmHg, 2.744 kPa) at 1 000 ml and55 cmH₂O (40.44 mmHg, 5.39 kPa) at 1 050 ml. There was a functional relationship between abdominal pressure and peritoneal volume: Y=0.164 2X-132 (r=0.896, t=4.504, P=0.006).

The liquid animal model of intra-abdominal hypertension can be successfully established by the improved superposition of water sac. The pressure-volume curve is a unidirectional curve, gradually increasing with the addition of intra-peritoneal solution. After exceeding the compensatory critical point, a small amount of intra-abdominal fluid can cause significant increase in abdominal pressure with a trend of sustained growth.