探讨泡沫硬化剂联合静脉旋切术治疗严重下肢静脉曲张的临床疗效。

收集2014年1月至2017年12月深圳大学第一附属医院（深圳市第二人民医院）共49例严重下肢静脉曲张（C4~C6级）患者，分为联合组（33例）和对照组（16例）。两组患者均先行大隐静脉高位结扎剥脱术，联合组采用泡沫硬化剂联合静脉旋切术，对照组则采用静脉旋切术。对两组术中出血量、术后疼痛时间、开始下床时间、住院时间、术后水肿发生率、其他并发症发生率进行比较。

联合组与对照组在术中出血量、术后疼痛时间、住院时间上差异均有统计学意义（t=3.916、3.465、2.554，P=0.003、0.001、0.011），在术后下床时间、术后水肿发生率、术后并发症发生率上差异无统计学意义（t=1.851，χ²=3.614、1.467，P=0.406、0.057、0.226）。

泡沫硬化剂联合静脉旋切术具有出血量少、术后恢复时间快、住院时间短等优点，可个体化用于严重下肢静脉曲张的临床治疗。

To investigate the clinical effect of combined treatment of the foam sclerotherapy and transilluminated powered phlebectomy (TIPP) of severe lower extremity varicose vein.

Forty-nine cases of varicosis of great saphenous vein were randomly divided into two groups: 33 cases in the combination group and 16 cases in the control group. The combination group underwent high ligation of great saphenous vein combined foam sclerotherapy and TIPP, while control group only high ligation of great saphenous vein combined TIPP.

There were significant differences between two groups in intraoperative blood loss, postoperative pain duration and hospitalization duration (t=3.916, 3.465, 2.554, P=0.003, 0.001, 0.011), but no significant differences in postoperative off-bed time, postoperative edema incidence and postoperative complication incidence (t=1.851, χ²=3.614, 1.467, P=0.406, 0.057, 0.226).

Foam sclerotherapy combined with TIPP shows less bleeding, postoperative recovery time, and shorter hospitalization time.