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中华普通外科学文献(电子版) ›› 2023, Vol. 17 ›› Issue (03) : 225 -230. doi: 10.3877/cma.j.issn.1674-0793.2023.03.014

综述

峡部甲状腺乳头状癌手术方式的研究现状
李永浩, 高雪菲, 郭田田, 张进, 刘静()   
  1. 030000 太原,山西医科大学第一临床医学院
    030000 太原,山西医科大学第一医院甲状腺外科
  • 收稿日期:2022-08-08 出版日期:2023-06-01
  • 通信作者: 刘静
  • 基金资助:
    山西省医学重点科技项目计划-引导性科技专项(2020XM57); "四个一批"山西省医学科技创新团队建设项目(甲状腺癌临床诊治和基础研究创新团队)(2020TD16)

Current status of surgical approaches for papillary thyroid carcinoma of the isthmus

Yonghao Li, Xuefei Gao, Tiantian Guo, Jin Zhang, Jing Liu()   

  1. The First Clinical School of Shanxi Medical University, Taiyuan 030000, China
    Department of Thyroid Surgery, the First Hospital of Shanxi Medical University, Taiyuan 030000, China
  • Received:2022-08-08 Published:2023-06-01
  • Corresponding author: Jing Liu
引用本文:

李永浩, 高雪菲, 郭田田, 张进, 刘静. 峡部甲状腺乳头状癌手术方式的研究现状[J]. 中华普通外科学文献(电子版), 2023, 17(03): 225-230.

Yonghao Li, Xuefei Gao, Tiantian Guo, Jin Zhang, Jing Liu. Current status of surgical approaches for papillary thyroid carcinoma of the isthmus[J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(03): 225-230.

近年来,甲状腺乳头状癌的发病率迅速上升,国内外指南对于腺叶甲状腺乳头状癌的手术方式已有较明确的说明,而峡部甲状腺乳头状癌因位置特殊且侵袭性较强,其手术切除范围在相关指南中尚未明确,仍存在争议。本综述通过检索近5年国内外相关文献,对峡部甲状腺乳头状癌的病理学特征、术前诊断和手术治疗等方面进行总结与分析,以期为临床工作提供参考。

In recent years, the incidence of papillary thyroid carcinoma has been rapidly increasing, and various guidelines at home and abroad have clearly stated the surgical approach for tumors located in the lobes of the gland, while the scope of surgical resection of papillary thyroid carcinoma located in the isthmus has not been clearly defined in the relevant guidelines due to its special location and strong invasion, and there is still controversy. This article summarizes and analyzes the pathological features, preoperative diagnosis and surgical treatment of papillary thyroid carcinoma of the isthmus by searching the relevant domestic and international literature in the past 5 years, with the aim of providing reference for clinical work.

[1]
Lyu YS, Pyo JS, Cho WJ, et al. Clinicopathological significance of papillary thyroid carcinoma located in the isthmus: A meta-analysis[J]. World J Surg, 2021, 45(9): 2759-2768.
[2]
Lim ST, Jeon YW, Suh YJ. Correlation between surgical extent and prognosis in node-negative, early-stage papillary thyroid carcinoma originating in the isthmus[J]. World J Surg, 2016, 40(2): 344-349.
[3]
Lee YS, Jeong JJ, Nam KH, et al. Papillary carcinoma located in the thyroid isthmus[J]. World J Surg, 2010, 34(1): 36-39.
[4]
Luo H, Yan F, Lan L, et al. Ultrasonographic features, nodule size, capsular invasion, and lymph node metastasis of solitary papillary carcinoma of thyroid isthmus[J]. Front Oncol, 2020, 10: 558363.
[5]
Feng JW, Qu Z, Qin AC, et al. Significance of multifocality in papillary thyroid carcinoma[J]. Eur J Surg Oncol, 2020, 46(10 Pt A): 1820-1828.
[6]
Bortz MD, Kuchta K, Winchester DJ, et al. Extrathyroidal extension predicts negative clinical outcomes in papillary thyroid cancer[J]. Surgery, 2021, 169(1): 2-6.
[7]
Seok J, Choi JY, Yu HW, et al. Papillary thyroid cancers of the thyroid isthmus: the pattern of nodal metastasis and the significance of extrathyroidal extension[J]. Ann Surg Oncol, 2020, 27(6): 1937-1944.
[8]
Park H, Harries V, McGill MR, et al. Isthmusectomy in selected patients with well-differentiated thyroid carcinoma[J]. Head Neck, 2020, 42(1): 43-49.
[9]
Zhang C, Li BJ, Liu Z, et al. Predicting the factors associated with central lymph node metastasis in clinical node-negative (cN0) papillary thyroid microcarcinoma[J]. Eur Arch Otorhinolaryngol, 2020, 277(4): 1191-1198.
[10]
Feng JW, Qu Z, Ye J, et al. Nomograms to predict ipsilateral and contralateral central lymph node metastasis in clinically lymph node-negative patients with solitary isthmic classic papillary thyroid carcinoma[J]. Surgery, 2021, 170(6): 1670-1679.
[11]
Zhou L, Gao C, Li H, et al. Isthmic papillary thyroid carcinoma presents a unique pattern of central lymph node metastasis[J]. Cancer Manag Res, 2020, 12: 3643-3650.
[12]
Gui Z, Wang Z, Xiang J, et al. Comparison of outcomes following thyroid isthmusectomy, unilateral thyroid lobectomy, and total thyroidectomy in patients with papillary thyroid microcarcinoma of the thyroid isthmus: A retrospective study at a single center[J]. Med Sci Monit, 2020, 26: e927407.
[13]
梁理娟, 蒙万添, 赖华强, 等. 彩色多普勒超声检查在甲状腺恶性肿瘤的诊断价值[J/CD].中华消化病与影像杂志(电子版), 2022, 12(5): 274-277.
[14]
郑祎, 詹维伟. 超声鉴别甲状腺峡部结节良恶性的研究[J/CD]. 中华医学超声杂志(电子版), 2020, 17(11): 1114-1120.
[15]
赵佳航, 张艳, 罗渝昆, 等. 超声与CT检查在诊断甲状腺乳头状癌颈部淋巴结转移中的对比分析[J]. 中国医学科学院学报, 2022, 44(1): 65-71.
[16]
韩志江, 谢乐斯, 魏培英, 等. CT对甲状腺乳头状癌被膜侵犯及颈部淋巴结转移的预测价值[J]. 中华放射学杂志, 2021, 55(7): 723-728.
[17]
Zhang X, Zhang X, Du W, et al. Fine needle biopsy versus core needle biopsy combined with/without thyroglobulin or BRAF 600E mutation assessment for detecting cervical nodal metastasis of papillary thyroid carcinoma[J]. Front Endocrinol (Lausanne), 2021, 12: 663720.
[18]
Prete A, Borges de Souza P, Censi S, et al. Update on fundamental mechanisms of thyroid cancer[J]. Front Endocrinol (Lausanne), 2020, 11: 102.
[19]
Zheng L, Liu FY, Yu J, et al. Thermal ablation for papillary thyroid microcarcinoma located in the isthmus: A study with 3 years of follow-up[J]. Future Oncol, 2022, 18(4): 471-480.
[20]
Horiguchi K, Yoshida Y, Iwaku K, et al. Position paper from the Japan Thyroid Association task force on the management of low-risk papillary thyroid microcarcinoma (T1aN0M0) in adults[J]. Endocr J, 2021, 68(7): 763-780.
[21]
Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer[J]. Thyroid, 2016, 26(1): 1-133.
[22]
中华人民共和国国家卫生健康委员会. 甲状腺癌诊疗规范(2018年版)[J/CD]. 中华普通外科学文献(电子版), 2019, 13(1): 1-15.
[23]
Nixon IJ, Palmer FL, Whitcher MM, et al. Thyroid isthmusectomy for well-differentiated thyroid cancer[J]. Ann Surg Oncol, 2011, 18(3): 767-770.
[24]
Campennì A, Piantanida R, Giovanella L. Is isthmic enucleo-resection a reliable treatment for isthmic differentiated thyroid carcinoma? A note of caution[J]. J Endocrinol Invest, 2020, 43(12): 1829-1830.
[25]
Huang H, Yan D, Liu W, et al. Isthmectomy is effective and sufficient for selected patients with the isthmus-confined solitary papillary thyroid carcinoma[J]. Asian J Surg, 2022, 45(9): 1678-1681.
[26]
Seo HW, Song CM, Ji YB, et al. Surgical outcomes and efficacy of isthmusectomy in single isthmic papillary thyroid carcinoma: A preliminary retrospective study[J]. J Invest Surg, 2021, 34(10): 1129-1134.
[27]
Goldfarb M, Rodgers SS, Lew JI. Appropriate surgical procedure for dominant thyroid nodules of the isthmus 1 cm or larger[J]. Arch Surg, 2012, 147(9): 881-884.
[28]
Lei J, Zhu J, Li Z, et al. Surgical procedures for papillary thyroid carcinoma located in the thyroid isthmus: An intention-to-treat analysis[J]. Onco Targets Ther, 2016, 9: 5209-5216.
[29]
Shuai Y, Yue K, Duan Y, et al. Surgical extent of central lymph node dissection for papillary thyroid carcinoma located in the isthmus: A propensity scoring matched study[J]. Front Endocrinol (Lausanne), 2021, 12: 620147.
[30]
Zhao J, Zhang Y, Zheng X. Clinicopathological characteristics of papillary thyroid cancer located in the isthmus with Delphian lymph node metastasis[J]. Br J Oral Maxillofac Surg, 2022, 60(5): 635-638.
[31]
Li G, Lei J, Peng Q, et al. Lymph node metastasis characteristics of papillary thyroid carcinoma located in the isthmus: A single-center analysis[J]. Medicine (Baltimore), 2017, 96(24): e7143.
[32]
Zhang LZ, Xu JJ, Ge XY, et al. Pathological analysis and surgical modalities selection of cT1N0M0 solitary papillary thyroid carcinoma in the isthmus[J]. Gland Surg, 2021, 10(8): 2445-2454.
[33]
黄煜庆, 温庆良, 曹君, 等. 峡部甲状腺乳头状癌120例临床病理学特征分析[J]. 肿瘤学杂志, 2018, 24(4): 308-312.
[34]
Zhao WJ, Luo H, Zhou YM, et al. Evaluating the effectiveness of prophylactic central neck dissection with total thyroidectomy for cN0 papillary thyroid carcinoma: An updated meta-analysis[J]. Eur J Surg Oncol, 2017, 43(11):1989-2000.
[35]
王梦一, 袁宏伟, 张宁, 等. 峡部甲状腺乳头状癌的诊治探讨[J]. 中华内分泌外科杂志, 2015, 9(1): 9-12.
[36]
Zhou B, Qin J. High-risk factors for lymph node metastasis in contralateral central compartment in unilateral papillary thyroid carcinoma(cT1N0)[J]. Eur J Surg Oncol, 2021, 47(4): 882-887.
[37]
Kwon O, Lee S, Bae JS, et al. Thyroid isthmusectomy with prophylactic central compartment neck dissection is a feasible approach for papillary thyroid cancer on the isthmus[J]. Ann Surg Oncol, 2021, 28(11): 6603-6612.
[38]
Du W, Fang Q, Zhang X, et al. Metastasis of cN0 papillary thyroid carcinoma of the isthmus to the lymph node posterior to the right recurrent laryngeal nerve[J]. Front Endocrinol (Lausanne), 2021, 12: 677986.
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