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中华普通外科学文献(电子版) ›› 2010, Vol. 04 ›› Issue (03) : 228 -231. doi: 10.3877/cma.j.issn.1674-0793.2010.03.011

所属专题: 经典病例 文献

论著

残胃复发癌30例的外科治疗及其预后分析
周军1, 江志鹏1, 杨斌1, 赖东明1, 张育超1, 李英儒1, 金杰波1, 陈双1,()   
  1. 1. 510120 广州,中山大学附属孙逸仙纪念医院胃肠外科
  • 收稿日期:2010-03-15 出版日期:2010-06-01
  • 通信作者: 陈双
  • 基金资助:
    教育部新教师基金资助项目(200805581125)

Surgical treatment and prognosis analysis of the remnant stomach relapse cancers

Jun ZHOU1, Zhi-peng JIANG1, Bin YANG1, Dong-ming LAI1, Yu-chao ZHANG1, Ying-ru LI1, Jie-bo JIN1, Shuang CHEN1,()   

  1. 1. Department of Gastrointestinal Surgery, Sun Yat-sen Memorial Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510120, China
  • Received:2010-03-15 Published:2010-06-01
  • Corresponding author: Shuang CHEN
  • About author:
    Corresponding Author: CHEN Shuang, Email:
引用本文:

周军, 江志鹏, 杨斌, 赖东明, 张育超, 李英儒, 金杰波, 陈双. 残胃复发癌30例的外科治疗及其预后分析[J]. 中华普通外科学文献(电子版), 2010, 04(03): 228-231.

Jun ZHOU, Zhi-peng JIANG, Bin YANG, Dong-ming LAI, Yu-chao ZHANG, Ying-ru LI, Jie-bo JIN, Shuang CHEN. Surgical treatment and prognosis analysis of the remnant stomach relapse cancers[J]. Chinese Archives of General Surgery(Electronic Edition), 2010, 04(03): 228-231.

目的

分析残胃复发癌的外科疗效和影响预后因素。

方法

对本院1993年1月至2007年12月间因胃癌根治术后复发再次接受外科手术的30例临床资料进行回顾性总结。用Kaplan-Meier和Cox回归模型行生存分析,Long-rank行有效性检验。

结果

总体平均生存期30.52个月,中位生存期25个月。其中根治性切除19例(63.3%),平均生存41.43个月,非根治性手术11例(36.7%),平均生存16.85个月(P<0.01)。Kaplan-Meier分析提示病理分期、病理类型、根治情况、有无腹膜种植、是否肝转移与生存期相关(P<0.01),而性别、年龄、复发距初次手术时间、化疗与否与生存期无关。

结论

临床分期、腹膜种植及根治性手术是影响残胃复发癌预后的主要因素,残胃复发癌的个体化治愈性切除仍可获得较好的疗效。

Objective

To investigate the surgical treat efficiency and the prognosis impact of the remnant stomach relapse cancers.

Methods

The clinical data of 30 cases with relapse stomach cancer accepted twice surgical operation were summarized retrospectively from January 1993 to December 2007. The statistical survival analyses were done by Kaplan-Meier and Cox regress model, the validity proof-test were analyzed by Long-rank.

Results

The total average life span were 30.52 months, the middle life span were 25 months. The life span of 19 cases(63.3%) received radical excision were 41.43 months, while 11 cases (36.7%) accepted non-radical excision could survive for 16.85 months medially(P<0.01). The life span were correlated with pathologic staging, diffuse-type, radical matter, peritoneal seeding, liver metastasis (P<0.01), but the factors including sex, age, the time between tumor relapse and the first operation and chemotherapy schedule were no correlated with the survival time.

Conclusions

Clinical staging, peritoneal implantation or radical excision matters are major factors impacting the prognosis of the remnant stomach relapse cancers. The therapeutic effect can still get with the individual healing excision.

表1 30例残胃复发癌的临床因素与生存期分析
1
Otsuji E, Kobayashi S, Okamoto K, et al. Is timing of death from tumor recurrence predicable after curative resection for gastric cancer. World J Surg, 2001, 25(11):1373-1376.
2
Roderich ES, Kathryn ZN. Recurrence pattern after radical gastrectomy for gastric cancer: Prognostic factors and implications for postoperative adjuvant therapy. Ann Surg Oncol, 2002, 9(4):394-400.
3
陈峻青.胃癌根治术后复发形式和方法的选择.中国实用外科杂志, 1995, 15(12):709.
4
Kunisaki C, Shimada H, Nomura M, et al. Lymph node dissection in surgical treatment for remnant stomach cancer. Hepato gastroenterology, 2002, 49(44):580-584.
5
Hye SA, Jong WK, Moon-Won Y, et al. Clinicopathological features and surgical outcomes of patients with remnant gastric cancer after a distal gastrectomy. Ann Surg Oncol, 2008, 15(6):1632.
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