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中华普通外科学文献(电子版) ›› 2016, Vol. 10 ›› Issue (04) : 273 -277. doi: 10.3877/cma.j.issn.1674-0793.2016.04.010

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论著

增强螺旋CT在进展期胃癌手术方案选择及可切除性评价中的价值
武赞凯1, 李龙1, 张耕源1, 龙勃1, 展昊1, 焦作义1,()   
  1. 1. 730000 兰州大学第二医院普外一科
  • 收稿日期:2016-04-02 出版日期:2016-08-01
  • 通信作者: 焦作义
  • 基金资助:
    中央高校基本科研业务费专项基金项目(lzujbky-2013-m04)

Value of contrast-enhanced CT in evaluating the surgical planning and resectability of advanced gastric cancer

Zankai Wu1, Long Li1, Gengyuan Zhang1, Bo Long1, Hao Zhan1, Zuoyi Jiao1,()   

  1. 1. Department of General Surgery, the Second Hospital Affiliated to Lanzhou University, Lanzhou 730000, China
  • Received:2016-04-02 Published:2016-08-01
  • Corresponding author: Zuoyi Jiao
  • About author:
    Corresponding authors: Jiao Zuoyi, Emial:
引用本文:

武赞凯, 李龙, 张耕源, 龙勃, 展昊, 焦作义. 增强螺旋CT在进展期胃癌手术方案选择及可切除性评价中的价值[J/OL]. 中华普通外科学文献(电子版), 2016, 10(04): 273-277.

Zankai Wu, Long Li, Gengyuan Zhang, Bo Long, Hao Zhan, Zuoyi Jiao. Value of contrast-enhanced CT in evaluating the surgical planning and resectability of advanced gastric cancer[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2016, 10(04): 273-277.

目的

探讨多层螺旋CT(MSCT)增强扫描在进展期胃癌术式选择以及可切除性判断中的应用价值。

方法

回顾性分析2013年2月至2015年3月收治的198例经手术病理证实为进展期胃癌的患者资料。所有患者术前均行常规CT平扫和增强扫描,结合患者CT诊断与手术及病理结果,比较两种扫描方法对进展期胃癌可切除性评估的准确性。

结果

185例行根治性切除,13例因术中发现不可切除因素行姑息性或腹腔镜探查手术。198例患者平扫、增强CT检出率分别为93.9%(186/198)、96.5%(191/198)。在手术切除范围、腹腔镜辅助及开腹选择、远处转移判断方面,平扫CT的准确性分别为87.6%(149/170)、82.3%(130/158)、63.6%(7/11),增强CT的准确性分别为93.1%(149/160)、92.9%(130/140)、72.7%(8/11),两者在腹腔镜辅助及开腹选择的差异有统计学意义(P=0.036)。平扫CT对进展期胃癌可切除判断的敏感度、特异度、准确性分别是89.2%(165/185)、23.1%(3/13)、84.8%(168/198),增强CT则分别为93.0%(172/185)、38.5%(5/13)、89.4%(177/198),两者差异有统计学意义(P<0.01)。

结论

MSCT增强扫描在判断切除范围,淋巴结及远处脏器转移方面准确性较高,在手术方式选择及腹腔镜辅助和开腹手术选择方面有重要参考价值,进而提高了进展期胃癌可切除性评估的准确性。

Objective

To compare the diagnostic performance of abdominal enhanced-contrast CT for the resectability of gastric cancer with conventional computed tomography (CT).

Methods

The traditional CT and enhanced CT images of patients with advanced gastric cancer were analyzed and the results in assessing resectability were compared. The diagnosis of advanced gastric cancer and resectability were confirmed by intraoperative findings and histopathology.

Results

One hundred and eighty-five cases underwent radical resection, and the other 13 were turned to palliative or laparoscopic exploration due to unresectable factors. The detection rates of conventional and enhanced CT were 93.9% (186/198) and 96.5% (191/198), respectively. The accuracy of conventional CT was 87.6%, 82.3% and 63.6% in the scope of surgical resection, operation choice and distant metastasis, and the accuracy of enhanced CT were 93.1%, 92.9%, 72.7%, respectively. There was a significant difference between the two groups (P=0.036). The sensitivity, specificity and accuracy of conventional CT and enhanced CT in the resection of advanced gastric cancer were 89.2%, 23.1%, 84.8% and 93.0%, 38.5%, 89.4% respectively, with a statistically significant difference (P<0.01).

Conclusion

Abdominal contrast-enhanced CT is more accurate for the resectability of gastric cancer, minimally invasive and better resectional range than conventional plain CT.

表1 MSCT对198例进展期胃癌患者手术方式选择及远处转移的评价(例)
图1 患者女,46岁,因"腹胀腹痛2月"入院,CT提示胃窦癌,拟行腹腔镜下根治性远端胃切除术,术中发现肿瘤已侵犯横结肠,中转开腹行联合部分结肠切除术(①、②CT图像中箭头所指为肿瘤位置,③手术图片中箭头所指为肿瘤侵犯横结肠处)
表2 平扫与增强CT对进展期胃癌可切除性评价结果
图2 患者女,44岁,因"腹胀腹痛1月余"入院,术前CT提示胃癌(胃窦、体部),拟行腹腔镜辅助下远端胃根治性切除,术中怀疑切缘阳性送冰冻回报:印戒细胞癌,后行根治性全胃切除术①、②增强CT图像中箭头所指为肿瘤;③为光学显微镜下观察术中切缘冰冻切片,结果示印戒细胞癌(HE染色,×40)
1
GLOBOCAN 2012: Estimated cancer incidence, mortality and prevalence worldwide in 2012[EB/OL]. [2013-12-12].

URL    
2
Kelley JR,Duggan JM. Gastric cancer epidemiology and risk fac-tors[J]. J Clin Epidemiol, 2003, 56(1): 1-9.
3
胡小生.腹腔镜胃癌手术现状与展望[J].江西医药, 2011, 46(8): 775-777.
4
Li Z. Indications of laparoscopic surgery for gastric cancer[J]. Zhonghua Wei Chang Wai Ke Za Zhi, 2014,17(8): 750-752.
5
王宋浩,陈严洁,陈树歆,等.进展期胃癌CT表现及术前评估价值分析[J].实用医学影像杂志, 2013, 14(3): 168-171.
6
武赞凯,王宇,张耕源,等.增强螺旋CT对进展期胃癌术前的评估价值[J/CD].中华普通外科学文献:电子版, 2016, 10(2): 133-137.
7
Chen CY,Hsu JS,Wu DC, et al. Gastric cancer: preoperative lo-cal staging with 3D multi-detector row CT--correlation with sur-gical and histopathologic results[J]. Radiology, 2007, 242(2): 472-482.
8
Filik M,Kir KM,Aksel B, et al. The Role of 18F-FDG PET/CT in the Primary Staging of Gastric Cancer[J]. Mol Imaging Radionucl Ther, 2015, 24(1): 15-20.
9
丁杰,廖国庆,晏仲舒,等.近端胃切除术和全胃切除术治疗胃底贲门癌的meta分析[J].中南大学学报(医学版), 2011, 36(6):570-575.
10
Chen BB,Liang PC,Liu KL, et al. Preoperative diagnosis of gas-tric tumors by three-dimensional multidetector row ct and double contrast barium meal study: correlation with surgical and histolog-ic results[J]. J Formos Med Assoc, 2007, 106(11): 943-952.
11
Kwee RM,Kwee TC. Imaging in local staging of gastric cancer: a systematic review[J]. J Clin Oncol, 2007, 25(15): 2107-2116.
12
Pan Z,Zhang H,Yan C, et al. Determining gastric cancer resect-ability by dynamic MDCT[J]. Eur Radiol, 2010, 20(3): 613-620.
13
Yoon H,Kim N. Diagnosis and management of high risk group for gastric cancer[J]. Gut Liver, 2015, 9(1): 5-17.
14
Cheong JC,Choi WH,Kim DJ, et al. Prognostic significance of computed tomography defined ascites in advanced gastric cancer[J]. J Korean Surg Soc, 2012, 82(4): 219-226.
15
Pongpornsup S,Neungton P,Chairoongruang S, et al. Diagnostic performance of multidetector computed tomography (MDCT) in evaluation for peritoneal metastasis in gastric cancer[J]. J Med As-soc Thai, 2014,97(8): 863-869.
16
Burbidge S,Mahady K,Naik K. The role of CT and staging lapa-roscopy in the staging of gastric cancer[J]. Clin Radiol, 2013, 68(3): 251-255.
17
Yajima K,Kanda T,Ohashi M, et al. Clinical and diagnostic sig-nificance of preoperative computed tomography findings of ascites in patients with advanced gastric cancer[J]. Am J Surg, 2006, 192(2): 185-190.
18
Funicelli L,Travaini LL,Landoni F, et al. Peritoneal carcinomato-sis from ovarian cancer: the role of CT and [18F]FDG-PET/CT[J]. Abdom Imaging, 2010, 35(6): 701-707.
19
Sarela AI,Lefkowitz R,Brennan MF, et al. Selection of patients with gastric adenocarcinoma for laparoscopic staging[J]. Am J Surg, 2006, 191(1): 134-138.
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