观察磺胺嘧啶银脂质水敷料促进肛周脓肿术后创面愈合的临床疗效。

选择2014年6月至2015年6月因肛周脓肿而行手术治疗的患者72例，随机双盲分为试验组和对照组各36例，试验组常规消毒后用磺胺嘧啶银脂质水敷料引流，对照组则常规消毒后用油纱引流。两组患者常规送脓液细菌培养，并比较两组创面疼痛程度及创面愈合时间的差异。

72例患者标本细菌培养阳性64例，总检出率88.9%。分离病原菌96株，其中革兰阴性菌占90.6%（87/96），革兰阳性球菌占9.4%（9/96）；混合感染占45.3%（29/96），以大肠埃希菌与其他细菌混合最常见；检出株数居首位的为大肠埃希菌占54.2%（52/96），其次为肺炎克雷伯菌，占16.7%（16/96）。试验组术后第4、6天疼痛评分（VAS）明显少于对照组，差异有统计学意义（t=3.64、3.61，均P<0.01）。试验组平均创面愈合天数分别为（24.5±4.7）d，明显短于对照组的（28.4±6.5）d，差异有统计学意义（t=2.92, P<0.05）。

肛周脓肿多为以革兰阴性杆菌为主的混合感染，应用磺胺嘧啶银脂质水敷料能有效减轻肛周脓肿术后创面疼痛，缩短创面愈合时间。

To study the effect of urgotul on postoperative perianal abscess.

A total of seventy two patients with perianal abscess enrolled in hospital from June 2014 to June 2015 were randomized in double-blind manner to trial group (36 cases) and control group (36 cases). The trial group patients were given urgotul to drain the exudates after operation, while the control group were treated with traditional disinfection. The pus of perianal abscess in the two groups were bacterially cultured. Post-operative pain and days of wound healing were also compared.

Bacterial culture was positive in 64 cases, with a total detection rate of 88.9%. Ninety-six strains of pathogens were isolated from the 72 patients, including 87 (90.6%) strains of gram-negative bacteria, 9 (9.4%) strains of gram-positive bacteria. Mixed infection accounted for 45.3% (29/96), and the most common was Escherichia coli mixed with other bacteria. Escherichia col were the top pathogens isolated, accounting for 54.2%, followed by Klebsiella pneumoniae of 16.7%. Patients in the trial group had less pain at 4, 6 d postoperatively (t=3.64, 3.61, both P<0.01). The days of wound healing in the trial group were significantly less than the control group [(24.5 ±4.7) d vs (28.4 ±6.5) d, t=2.92, P<0.05)].

Perianal abscess is mainly mixed infection with gram-negative bacterial. Urgotul can relieve the postoperative pain of patients with perianal abscess and reduce the days of wound healing.