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中华普通外科学文献(电子版) ›› 2023, Vol. 17 ›› Issue (05) : 391 -394. doi: 10.3877/cma.j.issn.1674-0793.2023.05.015

综述

胆囊癌肿瘤标志物的研究和应用进展
闫甲, 刘双池, 王政宇()   
  1. 233000 蚌埠医学院附属蚌埠第三人民医院肝胆外科
  • 收稿日期:2023-05-10 出版日期:2023-10-01
  • 通信作者: 王政宇
  • 基金资助:
    蚌埠医学院自然科学重点项目(2022byzd096)

Progress in the research and application of tumor markers for gallbladder cancer

Jia Yan, Shuangchi Liu, Zhengyu Wang()   

  1. Department of Hepatobiliary Surgery, the Third People’s Hospital Affiliated to Bengbu Medical College, Bengbu 233000, China
  • Received:2023-05-10 Published:2023-10-01
  • Corresponding author: Zhengyu Wang
引用本文:

闫甲, 刘双池, 王政宇. 胆囊癌肿瘤标志物的研究和应用进展[J]. 中华普通外科学文献(电子版), 2023, 17(05): 391-394.

Jia Yan, Shuangchi Liu, Zhengyu Wang. Progress in the research and application of tumor markers for gallbladder cancer[J]. Chinese Archives of General Surgery(Electronic Edition), 2023, 17(05): 391-394.

胆囊癌恶性程度高、侵袭性强、预后差,只有部分胆囊癌患者可以接受根治性手术治疗。近年来,肿瘤标志物的相关研究发展迅速,探索新的治疗靶点和肿瘤相关标志物为胆囊癌的检测、诊断及治疗提供了巨大帮助。伴随着液体活检、基因测序等技术的进步,肿瘤标志物的应用范畴得以拓宽,靶向联合免疫治疗成为胆囊癌治疗的新方式,这为胆囊癌的精准医疗奠定了基础。

Gallbladder cancer is highly malignant, aggressive and shows poor prognosis. Only part of patients with gallbladder cancer can receive radical surgery. In recent years, the research on tumor markers has developed rapidly, and the exploration of new therapeutic targets and tumor related markers has provided great assistance for the detection, diagnosis and treatment of gallbladder cancer. At the same time, with the advancement of liquid biopsy, gene sequencing and other technologies, the application scope of tumor markers have been broadened, and targeted combination immunotherapy has become a new treatment method for gallbladder cancer, laying the foundation for the precision medicine of gallbladder cancer.

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