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中华普通外科学文献(电子版) ›› 2025, Vol. 19 ›› Issue (03) : 183 -187. doi: 10.3877/cma.j.issn.1674-0793.2025.03.007

综述

精氨酸和谷氨酰胺在胃癌治疗中的应用及研究进展
陈使功1, 王文静2, 黎秀兰3, 龙勃1, 焦作义1,()   
  1. 1. 730030 兰州,兰州大学第二医院普通外科
    2. 730030 兰州,甘肃省中心医院心血管内科
    3. 410000 长沙,湖南省人民医院消化内镜一部
  • 收稿日期:2024-11-24 出版日期:2025-06-01
  • 通信作者: 焦作义
  • 基金资助:
    高校教师创新基金项目(2024B-020)自然科学基金项目(25JRRA619)

Application and research progress of arginine and glutamine in gastric cancer treatment

Shigong Chen1, Wenjing Wang2, Xiulan Li3, Bo Long1, Zuoyi Jiao1,()   

  1. 1. Department of General Surgery, the Second Hospital of Lanzhou University, Lanzhou 730030, China
    2. Department of Cardiology, Gansu Provincial Central Hospital, Lanzhou 730030, China
    3. Center of Digestive Endoscopy, Hunan Provincial People’s Hospital,Hunan Normal University, Changsha 410000, China
  • Received:2024-11-24 Published:2025-06-01
  • Corresponding author: Zuoyi Jiao
引用本文:

陈使功, 王文静, 黎秀兰, 龙勃, 焦作义. 精氨酸和谷氨酰胺在胃癌治疗中的应用及研究进展[J/OL]. 中华普通外科学文献(电子版), 2025, 19(03): 183-187.

Shigong Chen, Wenjing Wang, Xiulan Li, Bo Long, Zuoyi Jiao. Application and research progress of arginine and glutamine in gastric cancer treatment[J/OL]. Chinese Archives of General Surgery(Electronic Edition), 2025, 19(03): 183-187.

胃癌是全球发病率和死亡率较高的恶性肿瘤,患者常伴有营养不良,影响术后恢复、化疗耐受性及预后。近年来,免疫营养作为增强免疫功能的营养干预方法,受到广泛关注。免疫营养不仅改善营养状态,还能调节免疫功能,减轻炎性反应,促进伤口愈合和肠道修复,辅助胃癌治疗。本文系统综述了精氨酸和谷氨酰胺在胃癌治疗中的应用及其对患者预后的影响,旨在为临床实践和研究提供参考,并探讨未来的研究方向。

Gastric cancer is one kind of malignant tumors with high global incidence and mortality rates.Patients with gastric cancer often experience malnutrition, which adversely affects postoperative recovery, chemotherapy tolerance, and overall prognosis.In recent years, immunonutrition, as a nutritional intervention method aimed at enhancing immune function, has gained widespread attention.Immunonutrition not only improves nutritional status, but also regulates immune function, reduces inflammatory responses,promotes wound healing and intestinal repair, and aids in the treatment of gastric cancer.This paper systematically reviews the application of arginine and glutamine in the treatment of gastric cancer and their impact on patients’ prognosis, trying to provide references for clinical practice and research while exploring future research directions.

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