To summarize and analysis the perioperative anesthesia management experience of 18 living donor liver transplantation cases.

A retrospective analysis about clinical data of 18 living donor liver transplantation cases from May 2007 to October 2008 in our hospital were made. Among these, 17 were male and 1 was female, including 9 cases of liver cancer, chronic severe hepatitis 9 cases of liver cirrhosis. All receptors were accepted right liver transplantation using piggyback operation.

All liver transplant surgery of 18 cases were successful. The operative time were (10.5±1.6) hours, anhepatic phases was (100±15) minutes. Intraoperation blood loss were (3240±268) ml. Neohepatic phase of liver hemodynamic parameters recovered quickly. In neohepatic phase and the end of anhepatic phases coagulation function improved significantly. Five cases appeared hypokalemia and 3 appeared hyperkalemia, 6 of them appeared hypocalcemia. Metabolic acidosis often occured in the operation, especially in the end of anhepatic phases and 1-5 minutes of neohepatic phase(P<0.05).

Anhepatic phases of living donor liver transplantation last a longer time. More attention should be paid to correct the hemodynamics and water-electrolyte imbalance due to ischemia reperfusion injury in neohepatic phase. The improvement of coagulation function, homestasis will be benefical to cases.