1 |
Nelson WJ,Nusse R.Convergence of Wnt,beta-catenin,and cadherin pathways.Science,2004,303(5663):1483-1487.
|
2 |
Dierick H,Bejsovec A.Cellular mechanisms of wingless/Wnt signal transduction.Curr Top Dev Bio1,1999,43:153-190.
|
3 |
Reya T,Clevers H.Wnt signalling in stem cells and cancer.Nature,2005,434(7035):843-850.
|
4 |
Haydon RC,Deyrup A,Ishikawa A,et al.Cytoplasmic and/or nuclear accumulation of the β-catenin protein is a frequent in human osteosarcoma.Int J Cancer,2002,102(4):338-342.
|
5 |
Kolligs FT,Bommer G,Goke B.Wnt/beta-catenin/tcf signaling:acritical pathway in gastrointestinal tumorigenesis.Digestion,2002,66(3):131-144.
|
6 |
Gordon MD, Nusse R. Wnt Signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem, 2006, 281 (32):22429-22433.
|
7 |
Krieghoff E,Behrens J,Mayr B.Nucleo-cytoplasmic distribution of{beta}-catenin is regulated by retention.J Cell Sci,2006,119(7):1453-1463.
|
8 |
He B,You L,Uematsu K,et al.A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells.Neoplasia,2004,6(1):7-14.
|
9 |
Mazieres J,You L,He B,et al.Wnt2 as a new therapeutic target in malignant pleural mesothelioma.Int J Cancer,2005,117(2):326-332.
|
10 |
Lee AY,He B,You L,et al.Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma.Oncogene,2004,23(39):6672-6676.
|
11 |
Suzuki H,Watkins DN,Jair KW,et al.Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.Nat.Genet,2004,36(4):417-422.
|
12 |
Kim J,You L,Xu Z,et al.Wnt inhibitory factor inhibits lung cancer cell growth.J Thorac Cardiovasc Surg,2007,133(3):733-737.
|
13 |
Tsuji T, Nozaki I, Miyazaki M, et al. Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas.Biochem Biophys Res Commun,2001,289(1):257-263.
|
14 |
Hoang BH, Kubo T, Healey JH, et al. Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway.Cancer Res,2004,64(8):2734-2739.
|
15 |
Shou J,Ali-Osman F,Multani AS,et al.Human Dkk-1,a gene encoding a Wnt antagonist,responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.Oncogene,2002,21(6):878-889.
|
16 |
Mikheev AM, Mikheeva SA, Maxwell JP, et al. Dickkopf-1 mediated tumor suppression in human breast carcinoma cells. Breast Cancer Res Treat,2008,112(2):263-273.
|
17 |
Shih IM,Yu J,He TC,et al.The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.Cancer Res,2000,60(6):1671-1676.
|
18 |
Luo W,Peterson A,Garcia BA,et al.Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J, 2007,26(6):1511-1521.
|
19 |
Rudin CM, Kozloff M, Hoffman PC, et al. Phase I study of G3139, a bcl-2 antisense oligonucleotide, combined with carboplatin and etoposide in patients with small-cell lung cancer.J Clin Oncol,2004,22(6):1110-1117.
|
20 |
Advani R,Peethambaram P,Lum BL,et al.A Phase II trial of aprin ocarsen,an antisense oligonucleotide inhibitor of protein kinase C alpha,administered as a 21-day infusion to patients with advanced ovarian carcinoma.Cancer,2004,100(2):321-326.
|
21 |
Green DW, Roh H, Pippin JA, et al. Beta-catenin antisense treatment decreases beta-catenin expression and tumor growth rate in colon carcinoma xenografts.J Surg Res,2001,101(1):16-20.
|
22 |
Veeramachaneni NK,Kubokura H,Lin L, et al. Downregulation of beta catenin inhibits the growth of esophageal carcinoma cells. J Thorac Cardiovasc Surg,2004,127(1):92-98.
|
23 |
Verma UN,Surabhi RM,Schmaltieg A,et al.Small interfering RNAs directed against betacatenin inhibit the in vitro and In vivo growth of colon cancer cells.Clin Cancer Res,2003,9(4):1291-1300.
|
24 |
Zeng G,Apte U,Cieply B,et al.siRNA-Mediated B-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival.Neoplasia,2007,9(11):951-959.
|
25 |
Cong F,Zhang J,Pao W,et al.A protein knockdown strategy to study the function of beta-catenin in tumorigenesis.BMC Mol Biol,2003,4:10.
|
26 |
Su Y, Ishikawa S, Kojima M, et al. Eradication of pathogenic beta-catenin by Skp1/Cullin/F box ubiquitination machinery. Proc Natl Acad Sci, 2003,100(22):12729-12734.
|
27 |
Liu J, Stevens J, Matsunami N, et al. Targeted degradation of beta-catenin by chimeric F-box fusion proteins. Biochem Biophys Res Commun, 2004,313(4):1023-1029.
|
28 |
Ning X,Sun S,Hong L,et al.Calcyclin-binding protein inhibits proliferation,tumorigenicity, and invasion of gastric cancer. Mol Cancer Res, 2007, 5(12):1254-1262.
|
29 |
van de Wetering M,Sancho E,Verweij C,et al.The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell,2002,111(29):241-250.
|
30 |
Stadeli R,Basler K.Dissecting nuclear Wingless signalling:recruitment of the transcriptional co-activator Pygopus by a chain of adaptor proteins.Mech Dev,2005,122(11):1171-1182.
|
31 |
Hecht A,Vleminckx K,Stemmler MP,et al.The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates.EMBO J,2000,19(8):1839-1850.
|
32 |
Emami KH,Nguyen C,Ma H,et al.A small molecule inhibitor of β-catenin/CREB-binding protein transcription[corrected].Proc Natl Acad.Sci,USA 101(34):12682-12687.
|