Abstract:

Objective

To investigate the clinicopathological features,main points of diagnosis and antidiastole,andtherapyofbreastsclerosingadenosis,providingareferencefortherightdiagnosisandtreatment.

Methods

Depending on the clinicopathological features,routine HE staining,immunohistochemistry (IHC), clinical characteristics,imageological appearance,the surgical therapy of 8 cases with breast bclerosing adenosis were analyzed during the past 15 years in the third and first affiliated hospital of SUN Yat-sen university.

Results

Eight patients could not be correctly diagnosed by ultralsound and mammogram.The pathological appearance of 5 patients were similar to tubular cancer,and needed IHC to discriminate.One patient with non-palpable breast lesion were operated accurately with the guide wire localization under molybdenum target.All lesions were removed with no recurrence after followed up for 0.5-4.0 years.

Conclusions

Imageological methods,such as ultrasound and molybdenum tarsget are not sensitive for the diagnosis of breast sclerosing adenosis.IHC staining of myoepitheliumis an important for the diagnosis of breast sclerosing adenosis demarcated with breast cancer.Non-palpable lesion of breastsclerosing adenosis can be surgically exsected with the guide wire localization under molybdenum target.

Key words: Breat diseases, Sclerosing adenosis, Pathologic,surgury, Wire localization, Operation