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Chinese Archives of General Surgery(Electronic Edition) ›› 2009, Vol. 03 ›› Issue (05): 27-30. doi: 10.3877/cma.j.issn.1674-0793.2009.05.009

• Original Articles • Previous Articles     Next Articles

Effects of early enteral nutrition on acute inflammatory response syndrome after operations for ob-structive jaundice

Qiang-pu CHEN1,(), Qing-hai GUAN1, Fan ZHANG1, Xu-tao LIN1, Qian HUANG1, Xing-yuan ZHANG1   

  1. 1.Department of Hepatobiliary Surgery, the Affilzated Hospital of Binzhau Medical College,Binzhou 256603, China
  • Received:2009-01-20 Online:2009-10-01 Published:2024-12-01
  • Contact: Qiang-pu CHEN

Abstract:

Objective

To observe the effects of early enteral nutrition (EN)on system inflammatory response syndrome (SIRS)after the operations for obstructive jaundice.

Methods

According to random table,60 cases of postoperative patients with obstructive jauncdice were divided into three groups accepting early enteral nutrition,parenteral nutrition or general IV infusion respectively.CRP,IL-6 and TNF-α were measured on the day before operation and on the postoperative day 1,3,5,7and 9.At the same time,the clinical conditions of patients with SIRS, MODS and postoperative complications were observed and analyzed.

Results

Patients in all groups had SIRS after operations.The levels of CRP,IL-6 and TNF-α on the day 3,5,7,9 after operations were lower in the EN group than those in the PN group and control group. The duration of SIRS in the EN group was significantly shorter than that in the PN group and control group.The morbidity of MODS and postoperative complications was lower significantly in the EN group than that in the PN group and contral group.

Conclusions

Early EN after operations on the patients with obstructive jaundice can positively modulate SIRS and decrease the morbidity of MODS and postoperative complications.

Key words: Obstructive jaundice; Surgical procedures; Enteral nutrition; Systemic inflammatory response syndrome; Multiply organ dysfunction syndrome

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