To investigate the treatment methods for gastrointestinal carcinoma cases combining active tuberculosis.

The clinic data of 9 cases with gastrointestinal carcinoma combining active tuberculosis were analyzed retrospectively.

After strengthening and combining tuberculotherapy of EIRP or IRP for 2 weeks, all patients were carried on radical resection for malignant lesions. After operation, isonicotinyl hydrazide or second echelon drug for tuberculosis was drop intravenously. When the patient could take medicine, the primary EIRP or IRP was used. There were two cases complicating pneumonia, no tuberculosis dissemination or death case. Seven cases received consolidation tuberculotherapy with IR when no acid-fast bacilli was found in expectoration after strengthening tuberculotherapy for 2 months. FOLFOX4 or CapeOX chemotherapy were safely applied in the 7 patients during consolidation tuberculotherapy stage, and no worsening tuberculosis case was met.

It is reasonable for patients with gastrointestinal carcinoma combining active tuberculosis to receive radical resection after enforcing tuberculotherapy for two weeks. Intravenous tuberculotherapy drug could be used after operation. EIRP or IRP would be administered when the patient could take medicine. Chemotherapy may be safely carried on at the time of consolidation tuberculotherapy.