Abstract:
Objective To investigate pre-treatment condition, mean survival time, survival rate, tumor progression condition, complications and treatment cost of transcatheter arterial chemoembolization(TACE), radiofrequency ablation(RFA) and orthotopic liver retransplantation(re-OLT).
Methods Retrospective analysis of 53 cases reported for intrahepatic recurrence after liver transplantation of our hospital, from Jan. 2004 to Jun. 2009. There were 3 patients received surgical resection, 22 for TACE, 18 for RFA and 10 for re-OLT. The pre-treatment condition, survival time, tumor progression condition, complications and treatment cost of the patients of surgical resection are investigated. Treatment effect of the patients received TACE, RFA and re-OLT were compared and analyzed.
Results Three patients received surgical resection. After 4-12 months follow-up, they had not been found complications and tumor progression, and they were still alive. The difference of mean survival time, survival rates and the tumor progression condition among TACE, RFA and re-OLT are considered no significant; But RFA was lower in severe degree of complication, especially the biliary complications, and the cost of treatment: RFA<TACE<re-OLT.
Conclusions The curative effect among TACE, RFA and re-OLT are similar to one other in curing the tumor recurrence of liver cancer after liver transplantation. RFA is much lower than TACE and re-OLT in severe degree of complication and the cost of treatment.
Key words:
Liver cancer,
Liver transplantation,
Recurrence treatment
Chun-hui QIU, Hui ZHAO, Hu-an CHEN, Ying-hua CHEN, Wei MENG, Chi XU, Shu-hong YI, Hua LI, Gen-shu WANG, Jian ZHANG, Yang YANG, Chang-jie CAI, Min-qiang LU, Gui-hua CHEN. Strategies of treatments for tumor recurrence of liver cancer after liver transplantation[J]. Chinese Archives of General Surgery(Electronic Edition), 2011, 05(04): 320-325.