Meta-analysis of the effect of glutamine on immune function in patients with gastric cancer in China

doi:10.3877/cma.j.issn.1674-0793.2011.04.020

Abstract

Abstract:

Objective

To study the impact of the glutamine parenteral nutrition on immufunction in the gastric cancer.

Methods

Clinical controlled trails including glutamine on immune function were collected from CBMdisc,CNKI and VIP from 2001 to 2010. The methodological quality of included studies was evaluated, and data analyses were performed with The Cochrane Collaboration's software RevMan 5.0.25.

Results

A total of four clinical controlled trials were included in the study. Meta analysis showed with using glutamine after the trial, the immune function of patients were enhanced, the CD4, CD4/CD8 ratios were 9.15, 0.51 (P<0.01).

Conclusion

Glutamine in parenteral nutrition for patients with gastric cancer can improve and enhance the immune function under stress.

Key words: Glutamine, Gastric cancer, Immune function, Meta-analysis

Wan-hong ZHANG, Chang-chun SU. Meta-analysis of the effect of glutamine on immune function in patients with gastric cancer in China[J]. Chinese Archives of General Surgery(Electronic Edition), 2011, 05(04): 343-346.

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URL: https://zhptwkxwx.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0793.2011.04.020

https://zhptwkxwx.cma-cmc.com.cn/EN/Y2011/V05/I04/343

Figures/Tables 5

References 10

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第一作者名字缩写	发表时间（年）	病例数		实验设计	随机化	盲法	组间均衡性
第一作者名字缩写	发表时间（年）	试验组	对照组	实验设计	随机化	盲法	组间均衡性
CZH^[2]	2007	30	30	RCT	未提及	未使用	良好
ZJY^[3]	2005	25	25	RCT	未提及	未使用	未提及
GYH^[4]	2006	36	36	RCT	未提及	未使用	良好
CR^[5]	2009	28	32	RCT	未提及	未使用	未提及

第一作者名字缩写	发表时间（年）	病例数		实验设计	随机化	盲法	组间均衡性
第一作者名字缩写	发表时间（年）	试验组	对照组	实验设计	随机化	盲法	组间均衡性
CZH^[2]	2007	30	30	RCT	未提及	未使用	良好
ZJY^[3]	2005	25	25	RCT	未提及	未使用	未提及
GYH^[4]	2006	36	36	RCT	未提及	未使用	良好
CR^[5]	2009	28	32	RCT	未提及	未使用	未提及

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