To discuss base of pathological sort and ultrasonic diagnosis in diameter ≥10 mm polypoid lesions of the gallbladder (PLG) risk factors of gallbladder malignant disease.

Clinical data of 84 cases with ultrasonic and surgery pathological examination of PLG in diameter≥10 mm were retrospectively analyzed. They were divided into malignant group and benign group diagnosis with operation and pathologic of PLG, ultrasonic diagnosis and pathologic sort, evaluate risk factor of the gallbladder malignant disease were analyzed.

For the 84 cases with PLG, the sensitivity of ultrasonic diagnosis was 98.81%, the specificity was 89.29% and the accuracy was 94.05%. The positive predictive value was 88.10% and the negative predictive value was 89.29%, the rate error diagnosis was 10.71%. Benign group were 40 cases (47.62%) , malignant group were 44 cases (52.38%) . Analyzed with index of two group, the malignant group were older (67.5 years vs. 45.5 years) , with gallbladder stone (27.27% vs. 12.50%) , single lesion (97.14% vs. 75.00%) , diameter (35.2 mm vs. 15.6 mm) , bounty of the floor (97.73% vs. 67.50%) , color Doppler flow imaging (CDFI) of high resistance artery (84.00% vs. 23.08%) and character and resistine index (RI) (≥0.60 vs. ≤0.35) and so on, P < 0.05.

Diagnosis of operation and pathology for PLG with the diameter ≥10 mm is higher accord with ultrasonic. Risk factors for malignant PLG aret≥60 age, single, bounty of the floor, diameter≥20 mm, CDFI show blood stream of artery, RI≥0.60 and gallbladder stone. Ultrasonic diagnosis may be an important method to evaluate and differentiate of gallbladder malignant disease.