Research progress of microRNA in invasion and metastasis of hepatitis B virus-related hepatocellular carcinoma

doi:10.3877/cma.j.issn.1674-0793.2014.02.015

Abstract

Abstract:

MicroRNA (miRNA) is a kind of single stranded small endogenous non-coding RNA. Growing evidence indicates that its abnormal expression may play an important role in many diseases, including hepatocellular carcinoma (HCC). Postoperative recurrence and metastasis are the main causes of death, and the infection of hepatitis B virus (HBV) is the most key risk factor for the development and progression of HCC. Numerous reports have demonstrated that the dysfunction of miRNA is associated with invasion and metastasis in HBV related HCC, which as a newer marker will have a bright prospect for prognosis and treatment for the disease.

Key words: miRNA, Hepatitis B virus, Hepatocellular carcinoma, Invasion and metastasis

Guodong Chen, Zijian Yu, Zonghai Huang. Research progress of microRNA in invasion and metastasis of hepatitis B virus-related hepatocellular carcinoma[J]. Chinese Archives of General Surgery(Electronic Edition), 2014, 08(02): 143-147.

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https://zhptwkxwx.cma-cmc.com.cn/EN/Y2014/V08/I02/143

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