To investigate the regional anatomy of the preperitoneal space in the laparoscopic totally extraperitoneal (TEP) inguinal hernia repair, and to define anatomical structure according to different regions.

By reviewing and analyzing the surgical records and data of one hundred and twenty patients with inguinal hernia from May 2013 to May 2015 in our hospital, we grasp the surgical elements: one skill/technique, two anatomies, three intervals, and four regions.

By anatomy order, all patients underwent operations with ultrasonic knife fine separation, veil strip blunt division and peritoneum incision technique, operation time lasting for 50-100 minutes and bleeding of 10-30 ml. The majority of patients had off-bed activities the first day postoperatively, without obvious pains and discomforts. The average length of hospital stay was (6±1) days. Postoperative follow-up lasted from 4 to 24 months, with two cases of seroma, one case of subcutaneous congestion, one case of a small amount of scrotal hematoma, an outer ring road hematoma, all improved after symptomatic treatment, and no severe complications were observed.

Laparoscopic TEP has little trauma, fast recovery, good incision, shortened length of hospital stay, with mixed patches and tissues mixed to enhance the intension significantly. It is consistent with the principles of inguinal hernia tension-free repair and the anatomy structure of the human physiology. Once the anatomy of the peritoneal membrane regional space and intergrating surgical techniques are mastered, the standardized operation will shorten the learning curve, ensure surgical safety and reduce complications. It is worthy of popularization and application in hospitals at different levels.