To observe the effect of the laparoscopy combined with choledochoscope and duodenoscopy in the treatment of elderly patients with cholecystolithiasis and choledocholithiasis, and to analyze the influence on inflammatory factors.

From January to December 2019, 100 elderly patients with cholecystolithiasis and choledocholithiasis were selected and randomly divided into the control group (50 cases) and the trial group (50 cases) from Daping Hospital Affiliated to Army Medicine University. The trial group was treated by laparoscopy combined with choledochoscopy and duodenoscopy, and the control group was treated with laparoscopic common bile duct exploration T-tube drainage. The operation conditions (operation time, intraoperative blood loss, operation success rate), postoperative recovery (gastrointestinal function recovery, drainage volume, drainage tube indwelling time, hospitalization time), postoperative complications, and inflammatory index levels before and after treatment were compared between the two groups.

There were no significant differences in blood loss and success rate between the two groups. Compared with the control group, the operation time of the trial group was significantly prolonged (P<0.001), the recovery time of gastrointestinal function, the indwelling time of drainage tube and the hospitalization time were significantly shortened, and the drainage volume was less on the 1st and 2nd day after operation (P<0.001). The incidence of postoperative complications in the trial group was significantly lower than that in the control group (4.00% vs 20.00%, χ²=6.061, P=0.014). After treatment, the inflammatory index levels of the two groups were significantly lower than those before treatment, and the trial group was significantly lower than the control group (P<0.01).

In the treatment of elderly patients with cholecystolithiasis and choledocholithiasis, transabdominal placement of nasobiliary drainage through laparoscopy combined with choledochoscope and duodenoscopy can obviously obtain higher success rate of operation, shorten the indwelling time of drainage tube, reduce the occurrence of postoperative complications, reduce postoperative inflammatory reaction, effectively shorten the hospitalization time of patients, and the effect is ideal.