To investigate the feasibility and safety of natural orifice specific extraction surgery (NOSES) for colorectal tumors in primary hospitals.

From January 2019 to December 2020, 67 cases of colorectal tumor undergoing NOSES in Zhongshan People’ s Hospital were retrospectively analyzed to explore the application value of NOSES.

All the cases successfully completed the operation. 46.3% (31/67) of the tumors were located in the rectum, 44.8% (30/67) in the sigmoid colon and 9.0% (6/67) in other parts. CRC-NOSESⅠin 7 cases (10.4%), type Ⅱ in 16 cases (23.9%), type Ⅳ in 7 cases (10.4%), type Ⅵ in 28 cases (41.8%), and types Ⅴ, Ⅶ, Ⅷ in 9 cases (13.4%). Specimens of 58 cases (86.6%) were removed through rectum and anus, and 9 cases (13.4%) were removed through vagina. The average hospital stay was (7±2.7) d after operation. 94.0% (63/67) of the patients were off bed within 48 hours, 85.1% (57/67) of the patients recovered anal exhaust within 72 hours, 89.6% (60/67) could take in liquid diet within 3 days. Anastomotic bleeding, anastomotic leakage and intestinal obstruction occurred in 2, 3 and 2 cases respectively.

It is safe and feasible to select suitable colorectal tumor cases to carry out NOSES. NOSES can reduce patients’ trauma, shorten hospital stay and accelerate patients’ rehabilitation, which is worthy to be carried out in primary hospitals.