Abstract:
Objective To explore the effect of improved enhanced recovery after surgery (ERAS) model in radical gastrectomy for stage Ⅲ gastric cancer.
Methods A total of 150 gastric cancer patients admitted to Cancer Hospital of Shantou University Medical College from January 2019 to January 2021 were prospectively selected and divided into two groups by random number table method, with 75 patients in each group. The control group received traditional ERAS, and the observation group received improved anesthesia regimen and fluid management mode based on traditional ERAS. Perioperative recovery, stress response, complications and relapsing readmission were observed.
Results The first exhaust time, ambulation time, defecation time and postoperative hospital stay in the observation group were better than those in the control group (P<0.05). The levels of CRP, WBC, PCT and other inflammatory stress response indexes in the two groups three days after operation were significantly higher than those before surgery (P<0.05), and the level in the observation group was significantly lower than that in the control group (P<0.05). There were no statistically significant differences in recovery time to anesthesia, the number of lymph node dissection, the total incidence of postoperative complications, recurrence rate, readmission rate and cumulative disease-free survival rate between the two groups.
Conclusion Improved application of ERAS in laparoscopic radical gastrectomy for stage Ⅲ gastric cancer can effectively reduce the patients’ stress response and intraoperative blood loss, shorten the bed-off time, and promote postoperative recovery.
Key words:
Stage Ⅲ gastric cancer,
Laparoscopes,
Accelerated rehabilitation surgery,
Improvement
Guixing Lin, Yezhong Zhuang, Jiarui Lin, Liyun Xu, Haokai Hu. Application of improved enhanced recovery after surgery model in radical gastrectomy for stage Ⅲ gastric cancer[J]. Chinese Archives of General Surgery(Electronic Edition), 2022, 16(02): 101-105.