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Chinese Archives of General Surgery(Electronic Edition) ›› 2023, Vol. 17 ›› Issue (05): 391-394. doi: 10.3877/cma.j.issn.1674-0793.2023.05.015

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Progress in the research and application of tumor markers for gallbladder cancer

Jia Yan, Shuangchi Liu, Zhengyu Wang()   

  1. Department of Hepatobiliary Surgery, the Third People’s Hospital Affiliated to Bengbu Medical College, Bengbu 233000, China
  • Received:2023-05-10 Online:2023-10-01 Published:2023-10-19
  • Contact: Zhengyu Wang

Abstract:

Gallbladder cancer is highly malignant, aggressive and shows poor prognosis. Only part of patients with gallbladder cancer can receive radical surgery. In recent years, the research on tumor markers has developed rapidly, and the exploration of new therapeutic targets and tumor related markers has provided great assistance for the detection, diagnosis and treatment of gallbladder cancer. At the same time, with the advancement of liquid biopsy, gene sequencing and other technologies, the application scope of tumor markers have been broadened, and targeted combination immunotherapy has become a new treatment method for gallbladder cancer, laying the foundation for the precision medicine of gallbladder cancer.

Key words: Gallbladder carcinoma, Tumor marker, Targeted therapy, Immunotherapy, Precision medicine

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