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Chinese Archives of General Surgery(Electronic Edition) ›› 2024, Vol. 18 ›› Issue (02): 137-141. doi: 10.3877/cma.j.issn.1674-0793.2024.02.014

• Review • Previous Articles    

Advances in the treatment of recurrence after curative liver resection for hepatocellular carcinoma

Yun Cong1, Guoyu Li2, Danni Wang3, Yingmei Shao1,4,()   

  1. 1. Department of Hepatobiliary Hydatid Disease Surgery Urumqi 830054, China
    2. Digestive Vascular Center Pancreatic Surgery Urumqi 830054, China
    3. Department of Dermatology and Venereology,the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China
    4. State Key Laboratory of Central Asian High-prealence Disease Etiology and Prevention, Xinjiang Medical University, Urumqi 830054, China
  • Received:2023-10-17 Online:2024-04-01 Published:2025-03-12
  • Contact: Yingmei Shao

Abstract:

The high rates of recurrence and metastasis after radical liver resection have always affected the survival rate and prognosis of patients with hepatocellular carcinoma (HCC).Therefore, it is vital to reduce the recurrence rates.Surgical treatment is still one of the most effective approaches for HCC recurrence.In recent years, systemic anti-tumor therapies, represented by targeted therapy and immune checkpoint inhibitors, have shown tremendous potential.Significant progress has also been made in independently local treatment and combination therapies, improving patients' disease-free survival and overall survival.This article reviews the latest development in surgical treatment, local treatment, antiviral therapy, and systemic anti-tumor therapy for HCC recurrence, providing a summary of experiential evidence for effective prevention and treatment of HCC recurrence.

Key words: Carcinoma, hepatocellular, Recurrence and metastasis, Prevention, Treatment, Hepatectomy

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