Treatment progress for recurrent pulmonary metastasis after pulmonary metastasectomy of colorectal cancer

doi:10.3877/cma.j.issn.1674-0793.2025.01.009

Abstract

Abstract:

Colorectal cancer （CRC） is one of the most common malignancies worldwide， with high rates of incidence and mortality， and lung is a frequent site of metastasis.Surgical resection remains the primary treatment for CRC patients with pulmonary metastases， yet postoperative pulmonary recurrence is common.This review provides an overview of recent advances in managing recurrent pulmonary metastasis following pulmonary metastasectomy in CRC， with a focus on local therapies （radiofrequency ablation， microwave ablation， stereotactic body radiation therapy and so on） and systemic therapies（such as chemotherapy， targeted therapy， immunotherapy）.Future researches should focus on optimizing individualized treatment strategies， identifying effective biomarkers， and enhancing multidisciplinary collaboration to improve patients' outcomes.The goal remains to boost long-term survival rates and quality of life while reducing treatment-related toxicity.

Key words: Colorectal surgery, Neoplasm metastasis, Recurrent pulmonary metastasis, Local therapy, Systemic therapy

Jinjie Huang, Yinan Li, Caiqin Wang, Xiaohui Huang, Rongchang Wang. Treatment progress for recurrent pulmonary metastasis after pulmonary metastasectomy of colorectal cancer[J]. Chinese Archives of General Surgery(Electronic Edition), 2025, 19(01): 50-54.

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