Abstract:
Objective To investigate pathological features and surgery treatments for thyroid carcinoma associated Hashimoto’s disease.
Methods Clinical data and pathology feature of 24 Hashimoto′s disease patients were reviewed. All of 24 patients had concurrent thyroid carcinoma and accepted surgical treatments at Sichuan Cancer Center from 1996 to 2008.
Results Among the 24 of all 187 patients (12.8%) , 16 cases had papillary thyroid carcinoma, 5 cases had follicular thyroid carcinoma, 3 cases had mixed papillary-follicular carcinoma. Seven cases (29.2%) suffered from micro thyroid carcinoma, six cases(25%) had bilateral cancer, and 13 cases(54.2%) developed central region lymph node metastasis. Selection of thyroid lobectomy, subtotal or total parathyroidectomy were made on basis of both pre-surgery data and in-surgery frozen section histological examination. Central region lymph nodes were removed in all cases.
Conclusions Hashimoto′s disease is preoperative diagnosed poorly, although has a high coexistence rate with thyroid carcinoma. Coexistence with micro type should be taken more caution. Comprehensive analysis with case history and the effects of fine needle aspiration and color Doppler ultrasonography have benefits on the preoperative diagnosis. Surgery procedure is the most effective.
Key words:
Hashimoto′s disease,
Thyroid carcinoma,
Diagnosis,
Surgery
Jin CHEN, Zhaohui WANG, Wei WANG. Clinical analysis of Hashimoto′s disease complicated with thyroid cancer[J]. Chinese Archives of General Surgery(Electronic Edition), 2010, 04(06): 521-523.