To investigate the clinical effect of endovascular therapy for acute lower extremity deep venous thrombosis(LEDVT).

The clinical data of 1068 patients treated from January 2000 to December 2010 were analysed retrospectively. There were 311 cases of central type, 549 mixed type and 208 calf DVT. Foot dorsal vein and femoral vein were punctured to obtain venogram respectively. An Inferior vena cava filter was prophylactic placed. Then mechanical aspiration thrombectomy was performed via ipsilateral vein; patients with stenosis(>50% ) or obstruction of iliac vein underwent venoplasty and stent placement. Residual thrombus underwent thrombolytic treatment postoperatively. Patients received endovascular therapy were given a short-term and medium-term follow-up evaluation.

The rate of thrombus removal was GradeⅠ65.45%, GradeⅡ25.75%, GradeⅢ 8.05%, Grade Ⅳ 0.75%, respectively. Total effective rate was 99.25%. Postprocedure 24 months follow-up, "Excellent" 76.06% , "Moderate" 16.41% , "Mild" 6.28%, "Poor" 1.25%. The stent patency rate was 88.62%.

Endovascular therapy for acute LEDVT, which can remove thrombus as soon as possible, restore the blood flow instantly, and shorten hospitalization, has a notable short- and medium-term clinical effect.