Effects of nutritional status on the quality of life of patients with gastric cancer in perioperative period

doi:10.3877/cma.j.issn.1674-0793.2013.05.017

Abstract

Abstract:

Objective

To investigate the nutritional status and quality of life (QOL) of patients with gastric cancer in perioperative period and to analyze the relationship between nutritional status and QOL.

Methods

A prospective study was performed. One hundred and thirty-five patients with gastric cancer were enrolled in this study. The nutritional status and quality of life, 1 day before operation and 10 days after operation, were assessed by the Scored Patient-Generated Subjective Global Assessment (PG-SGA) and the Quality of Life Questionnaire of Stomach 22 (QLQ-STO22). Statistical analysis was performed using SPSS13.0 software.

Results

In preoperative period, the PG-SGA score was (6.71±3.05), which belonged to moderate malnutrition. PG-SGA score in postoperative period was (12.82±2.85), which belonged to severe malnutrition. PG-SGA score in postoperative period was significantly higher than that in preoperative period (t=-21.91, P=0.000). QOL score in postoperative period (19.69±7.59) was significantly higher than that in preoperative period (14.32±5.97) (t=8.21, P=0.000). The total scores of QOL showed statistically significant differences in patients with different nutritional statuses (F=29.29, P=0.000).

Conclusions

Gastric cancer patients' nutritional status and QOL are impaired in perioperative period. Compared with preoperative period, the nutritional status and QOL of postoperative period are obviously poorer. The QOL of malnourished patients is worse than well-nourished patients. Therefore, nutritional status is independently and negatively associated with QOL in gastric cancer and improving the status of nutritional should be viewed as an important part in the management of gastric cancer.

Key words: Gastric cancer, Perioperative, Nutritional status, Quality of life

Shi-ju HUANG, Xue-ling ZHOU, Hui-juan LI, Yun-e YANG, Xiao-lan HE, Zong-heng ZHENG. Effects of nutritional status on the quality of life of patients with gastric cancer in perioperative period[J]. Chinese Archives of General Surgery(Electronic Edition), 2013, 07(05): 400-403.

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References 8

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PG-SGA	PG-SGA总分	患者情况自评分	疾病状态评分	代谢应激评分	体格检查评分
术前1 d	6.71±3.05	1.69±1.26	1.45±1.86	0.05±0.31	1.37±1.30
术后10 d	12.82±2.85	2.60±1.07	2.29±0.46	0.97±0.46	1.96±1.47
t值	-21.91	-9.51	-5.32	-16.44	-8.74
P值	0.000	0.000	0.000	0.000	0.000

PG-SGA	PG-SGA总分	患者情况自评分	疾病状态评分	代谢应激评分	体格检查评分
术前1 d	6.71±3.05	1.69±1.26	1.45±1.86	0.05±0.31	1.37±1.30
术后10 d	12.82±2.85	2.60±1.07	2.29±0.46	0.97±0.46	1.96±1.47
t值	-21.91	-9.51	-5.32	-16.44	-8.74
P值	0.000	0.000	0.000	0.000	0.000

QLQ-STO22	总分	焦虑维度	疼痛维度	口干	反流症状维度
术前1 d	14.32±5.97	32.51±17.68	25.27±13.97	16.12±20.66	15.57±15.03
术后10 d	19.69±7.59	34.57±15.93	18.10±8.68	31.85±21.50	13.83±11.63
t值	8.21	1.50	-9.59	8.07	-1.74
P值	0.000	0.136	0.000	0.000	0.084
QLQ-STO22	吞咽困难维度	进食受限维度	脱发	躯体形象	味道改变
术前1 d	11.57±14.03	9.22±11.18	8.33±15.08	1.91±9.87	1.64±7.24
术后10 d	40.08±12.81	9.44±11.87	7.14±13.93	3.95±16.32	5.68±14.99
t值	25.86	0.22	-0.45	1.45	3.13
P值	0.000	0.827	0.656	0.149	0.002

QLQ-STO22	总分	焦虑维度	疼痛维度	口干	反流症状维度
术前1 d	14.32±5.97	32.51±17.68	25.27±13.97	16.12±20.66	15.57±15.03
术后10 d	19.69±7.59	34.57±15.93	18.10±8.68	31.85±21.50	13.83±11.63
t值	8.21	1.50	-9.59	8.07	-1.74
P值	0.000	0.136	0.000	0.000	0.084
QLQ-STO22	吞咽困难维度	进食受限维度	脱发	躯体形象	味道改变
术前1 d	11.57±14.03	9.22±11.18	8.33±15.08	1.91±9.87	1.64±7.24
术后10 d	40.08±12.81	9.44±11.87	7.14±13.93	3.95±16.32	5.68±14.99
t值	25.86	0.22	-0.45	1.45	3.13
P值	0.000	0.827	0.656	0.149	0.002

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