To investigate the effect of applying microbial enteral nutrition to patients with intra-abdominal infection.

From July 2011 to July 2014, the clinical data of 130 cases of abdominal infection were analyzed. The patients underwent surgical treatment and were divided into two groups randomly. Sixty-five cases were given normal enteral nutrition therapy as control group, and 65 patients were given microbial enteral nutrition therapy as the observation group. The natural killer cells (NK cells) and T cell subsets in both groups were tested before surgery, 3 and 7 days after surgery. The complications of the two groups were recorded.

Before surgery and the third day after surgery, the CD3, CD4, CD8, CD4/CD8 and NK cell levels of the two groups were not significantly different. One week after surgery, indicators as CD3, CD4, CD4/CD8 and NK cells, patients in observation group were (63±10)%, (40±10)%, 1.81±0.2, (20±5)%, higher than patients in control group [(56±9)%、(29±8) %、1.34±0.1、(14±3%) ], the differences between the groups were statistically significant (P<0.05). The incidence of complications rate in the observation group was lower than that in the control group (20% vs 40%, χ²=6.190, P=0.013).

By applying microbial enteral nutrition in patients with intra-abdominal infections, postoperative immune disorders can be improved, and the incidence of postoperative complications can be reduced, indicating its important clinical reference value.