To investigate the clinical efficacy of ultrasound-guided percutaneous transhepatic cholangial drainage (PTCD) in the treatment of hepatic alveolar echinococcosis with obstructive jaundice.

Eighty cases of hepatic alveolar echinococcosis with obstructive jaundice were treated in the Seventh Hospital of Wuhan from April 2013 to April 2017. Ultrasound guided PTCD therapy was performed. The general situation and adverse reaction of the patients were recorded, and the changes of liver function index and quality of life (QOL) were analyzed and compared.

The success rate of patients with disposable puncture was 93.75% (75/80), the average operation time was (36.31±8.57) min, the amount of hemorrhage of (30.25±18.62) ml, hospitalization time was (5.25±2.12) d, the average daily postoperative biliary drainage (507.34±86.54) ml, retention time of puncture tube was (85.75±12.54) d. No complications such as bile duct bleeding or septicemia were found. Compared with the preoperative indexes, total bilirubin (TBIL), direct bilirubin (DBIL), glutamyl transpeptidase (GGT), alkaline phosphatase (ALP), aspartate transaminase (AST), alanine aminotransferase (ALT), albumin (ALB) expression levels at 3 days, 1 week and 3 months after surgery were significantly lower, and the expression level of each index decreased gradually with the prolongation of treatment time (all P<0.05). The total score of QOL was (20.87±0.85), (32.85±3.61), and (45.63±5.78) respectively, which were significantly higher than those before treatment (14.54±0.62), the differences were statistically significant (P<0.05).

Ultrasound guided PTCD can improve the liver function and obstructive jaundice, enhance QOL and reduce the incidence of adverse reactions in the treatment of patients with hepatic alveolar echinococcosis.