Mechanism of eRF3a/GSPT1 in tumor initiation and progression

doi:10.3877/cma.j.issn.1674-0793.2019.03.018

Abstract

Abstract:

As a member of the eukaryotic peptide chain release factor family, eRF3a plays an important role in a variety of biological processes. It is encoded by the G1 to S phase transition 1 gene (GSPT1). In recent years, increasing evidence has indicated that eRF3a/GSPT1 is related to initiation and development of the common tumors. This paper is dedicated to depicting the roles of eRF3a/GSPT1 in the tumor development.

Key words: Eukaryotic cells, Peptide chain termination, Neoplasms, Molecular mechanisms of pharmacological action

Yiqing Xi, Lijie Yang, Danwen Wang, Zhangshuo Yang, Maohui Feng, Wei Xie. Mechanism of eRF3a/GSPT1 in tumor initiation and progression[J]. Chinese Archives of General Surgery(Electronic Edition), 2019, 13(03): 249-252.

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URL: https://zhptwkxwx.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-0793.2019.03.018

https://zhptwkxwx.cma-cmc.com.cn/EN/Y2019/V13/I03/249

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