To investigate the clinical effect of dexmedetomidine combined with ultrasound-guided sacral canal block in the high ligation of laparoscopic hernia sac in children.

90 cases of children undergoing laparoscopic high ligation of hernia sac in Lu’an People’s Hospital from January 2018 to December 2019 were prospectively included. All the children were divided into two groups by random number method. The conventional group received sacral block anesthesia with ropivacaine, and the combination group received sacral block anesthesia with dexmedetomidine plus ropivacaine. The operative time, recovery time、observation time in the resuscitation room and maintenance time of analgesia were compared between the two groups. Hemodynamics, including heart rate and mean arterial pressure, were compared between the two groups at pre-anesthesia (T₁), post-sacral block (T₂), dermectomy (T₃), surgical completion (T₄), tracheal catheter removal (T₅), and 10 minutes after resuscitation (T₆). The agitation of the two groups during the waking period was compared, including the incidence of agitation and the agitation score.

There were no significant differences in operation time, recovery time and observation time in recovery room between the two groups. The analgesia maintenance time in the conventional group was significantly shorter than that of the combination group (P<0.05). There were no significant differences in HR and MAP between the two groups at T₁. HR of the combination group was significantly lower than that of the conventional group from T₃ to T₅ (P<0.05). MAP level in the combination group was lower than that of the conventional group at T₅-T₆ (P<0.05). The incidence of restlessness in the conventional group was 22.2%, which was significantly higher than that of the combination group (6.7%) (P<0.05). The agitation score of the combination group was significantly lower than that of the conventional group (P<0.05).

The application of dexmedetomidine combined with ultrasound guided anesthesia in the high ligation of laparoscopic hernia sac in children can reduce the stress response of the body during the operation, maintain a more stable hemodynamic state, effectively reduce the occurrence of postoperative agitation during the recovery period, and improve the quality of the recovery period.