Abstract:

Objective

To compare the value of magnetic resonance imaging （MRI） and computed tomography （CT） in the diagnosis of peripancreatic vascular invasion in pancreatic ductal adenocarcinoma（PDAC）.

Methods

Eighty-two patients with PDAC diagnosed pathologically by surgical resection or laparotomy in the First Affiliated Hospital of Sun Yat-sen University from June 2019 to May 2022 were selected.Among them， 25 cases with vascular invasion and 57 cases without vascular invasion were confirmed according to the surgical results.All patients were examined by MRI and CT.The diagnostic efficacy of the two modalities for peripancreatic arterial and venous invasion was evaluated separately.The diagnostic differences between the results of one modality alone and the combination of the two modalities were compared.

Results

The differences in sensitivity and specificity between MRI and CT in assessing venous invasion were not statistically significant， while the aera under the curve （AUC） of MRI was better than CT （P＜0.05）； the differences in sensitivity and judgment between MRI and CT in assessing arterial invasion were not statistically significant， while the specificity of MRI was better than that of CT （P＜0.001）.When MRI was combined with CT， the sensitivity of assessment was increased and the judgment ability of vascular invasion was better than CT （P＜0.05）.

Conclusion

MRI is more suitable than CT for assessing peripancreatic venous invasion in PDAC， and combination of MRI with CT can improve the diagnostic sensitivity of vascular invasion in PDAC.

Key words: Carcinoma， pancreatic ductal, Magnetic resonance imaging, Tomography， X-Ray computed, Peripancreatic vascular invasion