Clinical-pathological feature and survival of gastric stump carcinoma: an analysis of 41 cases

doi:10.3877/cma.j.issn.1647-0793.2013.03.009

Abstract

Abstract:

Objective

To study the clinical feature and prognosis of gastric stump carcinoma (GSC).

Methods

A retrospective study was performed by following GSC cases diagnosed at the First Affiliated Hospital of Sun Yat-sen University between January, 1998 and February, 2010. The clinical feature and potential prognostic factors were analyzed.

Results

Forty-one GSC cases (male 37, 90.24%) were collected, with a 66-year median age, and an average 25-year interval between primary operation and GSC occurrence, which was negatively correlated with aging (P = 0.003). The younger of GSC patients, the higher of pathological stages and the lower of the differentiation degrees (P = 0.004). Most GSC was complicated with lymph nodes metastasis (60.98%). The 5-year survival rate was 37.00%. Cox proportional hazards model for survival analysis indicated that the clinical-pathological stage significantly affected survival and prognosis.

Conclusion

Regular gastroscopy is important to improve the quality of life in patients accepted subtotal gastrectomy.

Key words: Gastric stump carcinoma, Clinical-pathological, Survival analysis

Yin LI, Yu-long HE, Shi-rong CAI, Ji CUI, Jian-hui CHEN, Dong-jie YANG, Li-feng LU. Clinical-pathological feature and survival of gastric stump carcinoma: an analysis of 41 cases[J]. Chinese Archives of General Surgery(Electronic Edition), 2013, 07(03): 201-205.

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Figures/Tables 6

References 15

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临床特征		残胃癌
年龄(岁)		48~80(65.10±7.20)
性别(男/女)		37/4
初次手术病因(例)		?
?	十二指肠溃疡	12
?	胃溃疡	25
?	复合性溃疡	4
病程（年）		10.92(24.98±10.92)
Borrmann分型(例)		?
?	Ⅰ(息肉型)	6
?	Ⅱ(溃疡型)	11
?	Ⅲ型(溃疡浸润型)	24
肿瘤部位(例)		?
?	吻合口	31
?	非吻合口	10
症状(例)		?
?	胃痛或上腹不适	30
?	餐后腹胀	8
?	呕吐	10
?	进食困难	6
?	血便	9
?	贫血、乏力、消瘦	5
病理组织学分型(例)		?
?	高分化腺癌	2
?	中分化腺癌	3
?	低分化腺癌	25
?	未分化癌	3
?	鳞状细胞癌	2
?	印戒细胞癌	6

临床特征		残胃癌
年龄(岁)		48~80(65.10±7.20)
性别(男/女)		37/4
初次手术病因(例)		?
?	十二指肠溃疡	12
?	胃溃疡	25
?	复合性溃疡	4
病程（年）		10.92(24.98±10.92)
Borrmann分型(例)		?
?	Ⅰ(息肉型)	6
?	Ⅱ(溃疡型)	11
?	Ⅲ型(溃疡浸润型)	24
肿瘤部位(例)		?
?	吻合口	31
?	非吻合口	10
症状(例)		?
?	胃痛或上腹不适	30
?	餐后腹胀	8
?	呕吐	10
?	进食困难	6
?	血便	9
?	贫血、乏力、消瘦	5
病理组织学分型(例)		?
?	高分化腺癌	2
?	中分化腺癌	3
?	低分化腺癌	25
?	未分化癌	3
?	鳞状细胞癌	2
?	印戒细胞癌	6

组织病理		例数
浸润程度		?
?	T1	1
?	T2	7
?	T3	27
?	T4	6
手术方式		?
?	姑息性切除	4
?	根治性切除	37
远处转移		?
?	M0	37
?	M1	4
肿瘤分期		?
?	Ⅰ期	4
?	Ⅱ期	23
?	Ⅲ期	9
?	Ⅳ期	5
淋巴结转移		?
?	N0	16
?	N1	15
?	N2	8
?	N3	2

组织病理		例数
浸润程度		?
?	T1	1
?	T2	7
?	T3	27
?	T4	6
手术方式		?
?	姑息性切除	4
?	根治性切除	37
远处转移		?
?	M0	37
?	M1	4
肿瘤分期		?
?	Ⅰ期	4
?	Ⅱ期	23
?	Ⅲ期	9
?	Ⅳ期	5
淋巴结转移		?
?	N0	16
?	N1	15
?	N2	8
?	N3	2

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