Abstract:
Objective
To evaluate the effects of early fracture fixation on hemodynamics following multiple firearm injuries.
Methods
5.8 mm bullets were shot to make various injuries.18 pigs were randomly divided into 3 groups（6 for each）.Group C（control group）had catheterization only.Group M was subjected to tangental fracture of parietal bone and comminuted fractures of bilateral femora.Group F was subjected the same injuries as group M and had early fracture fixation with intramedullary nailing.The hemodynamic changes，including MAP，PAP，PAWP，CO，SVRI，portal vein blood flow and gastric intramucosal pH，were observed at different time intervals after trauma.
Results
No significant changes in all variables was found in the control group.In group M，hyperdynamic circulation emerged at 72 hours.The cardiac output rise and SVRI declined.Portal vein blood flow and gastric pH declined markedly.In group F，MAP had a temporary drop and PAP had a rise at 6 hours following trauma.The hemodynamic data returned to baseline promptly at 24 hours and did not change significantly.
Conclusion
Hemodynamic changes after multiple firearm injuries could be improved by early fracture fixation.
Key words:
Pigs,
Multiple firearm injuries,
Early fracture fixation,
Hemodynamics
Xing-dong YANG, Zhan-liang LI, Shi-he WU, Ying-xiang YANG. Early fracture fixation improved the changes in hemodynamics following multiple firearm injuries in a porcine model[J]. Chinese Archives of General Surgery(Electronic Edition), 2007, 01(04): 204-207.