To preliminary explore the value of CT perfusion for evaluating pre-operative hepatic functional reserve of primary liver cancer complicated with hepatic fibrosis.

The test group included 18 cases of primary liver cancer complicated with hepatic fibrosis of S₁-S₄. The control group included 10 cases of healthy. All patients were given preoperative heptic CT perfusion scan for screening a sensitive parameter of CTP when hepatic parenchyma had fibrosis of S₁-S₄. To analyse relationship of dysfunction and the parameter of CTP combinating Child-Pugh classification and STELV.

Before operation, all patients in the test group were in A geade. The degree of hepatic parenchyma was all in the degree of S₁-S₄. Through preoperative CT scan, obvious change of cirrhosis in shape and profile was not found. The data of HPP, HAP, TLP and PPI were (85.94±6.00) ml·min^-1·100g^-1, (27.89±4.74) ml·min^-1·100g^-1, (113.83±2.39) ml·min^-1·100g^-1 and (0.75±0.10)%. That of the control group were (93.5±9.56) ml·min^-1·100g^-1, (25.10±2.85) ml·min^-1·100g^-1, (118.60±7.53) ml·min^-1·100g^-1 and (0.78±0.11)%. HPP of the test group was significant lower than the control group. TLP, HAP and PPI of the test group were not significant difference comparing with those of the control group. In the base of Child-Pugh A after operation, we put HPP and STELV as discriminant indicators and the emergence of hepatic dysfunction as discriminant result. Two discriminant equations were got: f₁=5.533X₁+375.418X₂-382.957; f₂=5.221X₁+354.685X₂-341.381. Wilks' Lambda value was 0.610, P<0.05.

HPP of CTP parameters can measure the change of blood flow in the degree of S₁-S₄. It can establish a sensible equations that can preliminary assess preoperative hepatic functional reserve of PLC.